FlyBase Allele Report: Dmel\mod[07570]

General Information

Symbol

Dmel\mod⁰⁷⁵⁷⁰

Species

D. melanogaster

Name

FlyBase ID

FBal0028438

Feature type

allele

Associated gene

Dmel\mod

Associated Insertion(s)

P{PZ}mod⁰⁷⁵⁷⁰

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Roman et al., 2000)

Mutagen

P-element activity

(Castrillon et al., 1993)

Progenitor genotype

Associated Insertion(s)

P{PZ}mod⁰⁷⁵⁷⁰

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{PZ}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:32,052,658..32,052,658 [+]

(Roman et al., 2000, Spradling et al., 1999, BDGP Project Members, 1994-1999, Castrillon et al., 1993)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell death | spermatogenesis (with mod^L8)

(Park et al., 2023)

male semi-sterile

male semi-sterile | recessive

(Roman et al., 2000)

male sterile (with mod^L8)

(Park et al., 2023, Roman et al., 2000)

male sterile | recessive

(Spradling et al., 1999)

Minute (with mod^L8)

(Roman et al., 2000)

Phenotype Manifest In

macrochaeta (with mod^L8)

(Roman et al., 2000)

nucleus | spermatogenesis (with mod^L8)

(Park et al., 2023)

spermatid (with mod^L8)

(Park et al., 2023)

spermatozoon | absent (with mod^L8)

(Park et al., 2023)

Detailed Description

Statement

Reference

85% of homozygous males are sterile. 100% of mod^L8/mod⁰⁷⁵⁷⁰ males are sterile.

(Roman et al., 2000)

Semi-sterile.

(Castrillon et al., 1993)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

mod^S095214

(Roman et al., 2000)

Comments

krz^S047819 and krz³ fully complement the male sterility of mod⁰⁷⁵⁷⁰. mod^S095214 fails to complement the male sterility of mod⁰⁷⁵⁷⁰.

(Roman et al., 2000)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

11795

ry⁵⁰⁶ P{PZ}mod⁰⁷⁵⁷⁰/TM3, ry^RK Sb¹ Ser¹

Notes on Origin

Discoverer

A. Spradling.

Comments

Complements: krz^S047819. Complements: krz³.

(Roman et al., 2000)

Complements: heph¹. Complements: heph².

(BDGP Project Members, 1994-1999)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

mod⁰⁷⁵⁷⁰

(Park et al., 2023, Ribot et al., 2022, Sorourian et al., 2014, Rathke et al., 2007, Mikhaylova et al., 2006)

mod^P1795

(Roman et al., 2000)

ms(3)07570

(Spradling et al., 1999)

ms(3)100EF⁰⁷⁵⁷⁰

(Meister and Braun, 1995.10, BDGP Project Members, 1994-1999)

ms(3)ry100EF

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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