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General Information
Symbol
Dmel\stgAR2
Species
D. melanogaster
Name
FlyBase ID
FBal0035718
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deletion beginning at site of P element insertion and extending beyond anon-99A.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Cycle 14 stgAR2/stgAR2 embryos contain no mitotic cells, and are composed entirely of large G2 cells.

Postblastoderm cell divisions are completely blocked in stgAR2 mutants.

Eye of adults heterozygous with stghwy show rough and reduced eyes, missing macrochaetae and ommatidia with one or more extra photoreceptor cells.

Embryos derived from germ line clones proceed through cycles 1-13 normally.

Transheterozygotes with stgknot are pharate adult lethal, the few escapers exhibit rough eyes, missing bristles and defective abdominal cuticle, and have low fertility.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Enhancer of
Statement
Reference
Suppressor of
Statement
Reference

stgAR2/stg[+] is a suppressor of visible phenotype of Scer\GAL4en-e16E, crolUAS.cMa

stgAR2/stg[+] is a suppressor of increased cell death phenotype of shtd1

stgAR2 is a suppressor | partially of visible phenotype of rux3

NOT Suppressor of
Statement
Reference

stgAR2/stg[+] is a non-suppressor of male sterile phenotype of rux8

Other
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The reduced size of the posterior compartment of the wing that is seen in animals expressing crolScer\UAS.cMa under the control of Scer\GAL4en-e16E is suppressed if they are also heterozygous for stgAR2.

When weeScer\UAS.cPa is driven by Scer\GAL4neur-P72 in stgAR2 animals exhibit severe bristle loss.

The block in cycle 14 mitosis and increased cell-size in cycle 14 embryos seen in stgAR2/stgAR2 embryos is suppressed by pUf68EP3058/pUf68EP3058. Unlike stgAR2 homozygotes, stgAR2; pUf68EP3058 double homozygotes survive embryogenesis and die between first and second instar.

Dominantly enhances the rough eye phenotype of CycEJP homozygotes. One copy of stgAR2 has no effect on the reduction in the number of cells entering S phase posterior to the morphogenetic furrow seen in CycEJP homozygotes. One copy of stgAR2 enhances the reduction in the number of mitotic cells posterior to the morphogenetic furrow seen in CycEJP homozygotes.

36% of ommatidia of rux3 are restored to wild type by stgRXT13 or stgAR2. Flies carrying rux8 in a heterozygous stg background show partial rescue of the rough-eye phenotype, but not the male sterility, at 18oC.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by

stgAR2 is partially rescued by stgt31.6

Comments

The postblastoderm cell division phenotype is partially rescued by stgt31.6; cell cycle progression is seen in a subset of the wild-type division pattern.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
Comments
Comments

Transcriptional null allelle.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (19)