Open Close
General Information
Symbol
Dmel\inII53
Species
D. melanogaster
Name
FlyBase ID
FBal0039447
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutant flies have an almost wild-type wing hair phenotype at 18oC.

Mild multiple wing hair phenotype at 25oC though not at 18oC.

Viable as a homozygote or a hemizygote. Weak thoracic bristle and wing hair phenotype. Percentage of dorsal wing surface cells that display abnormal cell polarity and the percentage of wing cells forming more than one hair is more severe at 29oC than 18oC.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

inII53 has visible phenotype, enhanceable by frtz3

Enhancer of
Statement
Reference

inII53 is an enhancer of visible phenotype of frtz3

Phenotype Manifest In
Enhanced by
Statement
Reference

inII53 has wing hair phenotype, enhanceable by frtz3

inII53 has wing hair & 1st posterior cell phenotype, enhanceable by fz24

inII53 has wing hair & 1st posterior cell phenotype, enhanceable by fzHD21

inII53 has wing hair & 1st posterior cell phenotype, enhanceable by fzhs.PP

inII53 has wing hair & 1st posterior cell phenotype, enhanceable by mwh[+]/mwh1

inII53 has wing hair & 1st posterior cell phenotype, enhanceable by pk1

inII53 has wing hair & 1st posterior cell phenotype, enhanceable by dsh1

inII53 has wing hair & 1st posterior cell phenotype, enhanceable by VangTbs42

Enhancer of
Statement
Reference

inII53 is an enhancer of wing hair | increased number phenotype of frtz3

inII53 is an enhancer of wing hair phenotype of frtz3

inII53 is an enhancer of wing hair phenotype of VangTbs42

NOT Suppressor of
Statement
Reference

in1/inII53 is a non-suppressor of wing hair | heat sensitive phenotype of fzhs.PP

Additional Comments
Genetic Interactions
Statement
Reference

At 18oC, inII53 frtz3 double mutants have strong mutant polarity and hair number phenotypes in the wing hairs (while either single mutant has an almost wild-type wing hair phenotype at this temperature).

Late gain of function phenotype of fzhs.PP is not suppressible by inII53/in1 or fy6.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Weak in allele.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
inII53
Name Synonyms
Secondary FlyBase IDs
    References (5)