FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\InR35
Open Close
General Information
Symbol
Dmel\InR35
Species
D. melanogaster
Name
FlyBase ID
FBal0042642
Feature type
allele
Associated gene
Dmel\InR
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Fernandez et al., 1995)
Mutagen
ethyl methanesulfonate
(Fernandez et al., 1995)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      InR35 has lethal | recessive | larval stage phenotype, suppressible by Tsc129

      (Gao and Pan, 2001)

      InR35 has decreased cell size | somatic clone phenotype, suppressible by Tsc129

      (Gao and Pan, 2001)
      NOT Suppressor of
      Statement
      Reference

      InR35/InR05545 is a non-suppressor of increased cell size | somatic clone phenotype of Ptendj189

      (Gao et al., 2000)
      Other
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      InR35/InR05545 is a non-suppressor of wing margin bristle | somatic clone phenotype of Ptendj189

      (Gao et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Tsc129, InR35 double mutant clones in the eye, show a similar size increase as seen in Tsc129 mutant clones alone. Tsc129 suppresses the lethality of homozygous InR35, allowing 6.6% animals to survive to adults.

      (Gao and Pan, 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      When in trans with Df(3R)e-D7 the lethal phenotype can be rescue by P{hs-inr}.

      (Fernandez et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      InR35
      inr35
      (Gao et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)