FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\enaGC10
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General Information
Symbol
Dmel\enaGC10
Species
D. melanogaster
Name
FlyBase ID
FBal0043040
Feature type
allele
Associated gene
Dmel\ena
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
gamma ray
(Gertler et al., 1995)
Progenitor genotype
Caused by aberration
Df(2R)enaGC10
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Some homozygous embryos exhibit thinning of longitudinal connectives, increased number of axons exciting the CNS from the longitudinal axons or failure of commissural axons to separate into anterior and posterior axon bundles. The overall organisation of the PNS is disrupted, spacing and organisation of the neurons is irregular and some clusters of neurons are mislocalised.

      (Gertler et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      ena[+]/enaGC10 is a non-enhancer of abnormal neuroanatomy | dominant phenotype of Gyc76CKG03723ex173

      (Ayoob et al., 2004)
      Suppressor of
      Statement
      Reference

      ena[+]/enaGC10 is a suppressor | partially of abnormal neuroanatomy phenotype of Df(2R)vg135/fra4

      (Forsthoefel et al., 2005)

      ena[+]/enaGC10 is a suppressor | partially of abnormal neuroanatomy phenotype of Abl4/Abl1, Df(3L)Fpa1/trioM89

      (Forsthoefel et al., 2005)

      ena[+]/enaGC10 is a suppressor | partially of abnormal neuroanatomy phenotype of Abl4/Abl1, Df(3L)Fpa1/trioIMP159.4

      (Forsthoefel et al., 2005)

      ena[+]/enaGC10 is a suppressor | partially of lethal phenotype of Df(3L)Fpa1/trioM89

      (Liebl et al., 2000)

      ena[+]/enaGC10 is a suppressor of lethal phenotype of Abl4/Abl1

      (Liebl et al., 2000)

      ena[+]/enaGC10 is a suppressor of lethal | prepupal stage phenotype of Abl4/Abl1, NrtM221/Nrt[+]

      (Liebl et al., 2000)

      ena[+]/enaGC10 is a suppressor of lethal | prepupal stage phenotype of Abl4/Abl1, faxM7/fax[+]

      (Liebl et al., 2000)

      ena[+]/enaGC10 is a suppressor of lethal | prepupal stage phenotype of Abl4/Abl1, trio[+]/trioM89

      (Liebl et al., 2000)
      NOT Suppressor of
      Statement
      Reference

      ena[+]/enaGC10 is a non-suppressor of abnormal neuroanatomy | dominant phenotype of Gyc76CKG03723ex173

      (Ayoob et al., 2004)
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      ena[+]/enaGC10 is a non-enhancer of larval intersegmental nerve phenotype of Gyc76CKG03723ex173

      (Ayoob et al., 2004)

      ena[+]/enaGC10 is a non-enhancer of larval abdominal segmental nerve phenotype of Gyc76CKG03723ex173

      (Ayoob et al., 2004)
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      ena[+]/enaGC10 is a non-suppressor of larval intersegmental nerve phenotype of Gyc76CKG03723ex173

      (Ayoob et al., 2004)

      ena[+]/enaGC10 is a non-suppressor of larval abdominal segmental nerve phenotype of Gyc76CKG03723ex173

      (Ayoob et al., 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      enaGC10
      (Ayoob et al., 2004)
      enbGC10
      Name Synonyms
      Secondary FlyBase IDs
        References (4)