FB2026_02 , released June 18, 2026
Allele: Dmel\RpS21k16804a
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General Information
Symbol
Dmel\RpS21k16804a
Species
D. melanogaster
Name
FlyBase ID
FBal0043430
Feature type
allele
Associated gene
Dmel\RpS21
Associated Insertion(s)
P{lacW}RpS21k16804a
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
Progenitor genotype
Associated Insertion(s)
P{lacW}RpS21k16804a
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      exacerbates  tauopathy
      modeled by Hsap\MAPTGMR.Ex.PJ
      (Ambegaokar and Jackson, 2011)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      RpS21[+]/RpS21k16804a is an enhancer of visible phenotype of Hsap\MAPTGMR.Ex.PJ

      (Ambegaokar and Jackson, 2011)
      NOT Suppressor of
      Statement
      Reference

      RpS21[+]/RpS21k16804a is a non-suppressor of visible phenotype of Scer\GAL4GMR.PU, Zzzz\CAGQ108.UAS

      (Ambegaokar and Jackson, 2011)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      RpS21[+]/RpS21k16804a is an enhancer of eye phenotype of Hsap\MAPTGMR.Ex.PJ

      (Ambegaokar and Jackson, 2011)
      NOT Suppressor of
      Statement
      Reference

      RpS21[+]/RpS21k16804a is a non-suppressor of eye phenotype of Scer\GAL4GMR.PU, Zzzz\CAGQ108.UAS

      (Ambegaokar and Jackson, 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of RpS21k16804a mildly enhances the apoptosis seen in flies overexpressing hid.

      (Ambegaokar and Jackson, 2011)
      Xenogenetic Interactions
      Statement
      Reference

      One copy of RpS21k16804a enhances the rough eye phenotype seen in flies expressing Hsap\MAPTGMR.Ex.PJ.

      One copy of RpS21k16804a does not suppress the rough eye phenotype seen in flies expressing Zzzz\CAGQ108.Scer\UAS under the control of Scer\GAL4GMR.PU.

      (Ambegaokar and Jackson, 2011)
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (3)
      Notes on Origin
      Discoverer

      I. Kiss.

      Comments
      Comments

      This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

      Complements: lilli00632. Complements: sytk05909.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      RpS21k16804a
      (Johns et al., 2018)
      l(2)03575k16804a
      oho23Bk16804a
      (Ambegaokar and Jackson, 2011, Christensen et al., 2008.12.28)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)