FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Awh16
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General Information
Symbol
Dmel\Awh16
Species
D. melanogaster
Name
FlyBase ID
FBal0044658
Feature type
allele
Associated gene
Dmel\Awh
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Curtiss and Heilig, 1997)
Mutagen
ethyl methanesulfonate
(Curtiss and Heilig, 1995)
Progenitor genotype
Awh1
(Curtiss and Heilig, 1995)
Cytology
Description

Construct: Amino acid replacement: C138. Mutation truncates the Awh@ protein 10 amino acids before the homeodomain.

(Curtiss and Heilig, 1997)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:3,860,196..3,860,197 [+]
Reported amino acid change:

C138term

Comment:

A 2bp deletion that changes Cys138 into a stop codon.

(Curtiss and Heilig, 1997)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Targeting of dendrites to antennal lobe glomeruli occurs normally in antennal lobe projection neurons which are part of Awh16 homozygous somatic clones.

      (Komiyama and Luo, 2007)

      Small eyes.

      (Curtiss and Heilig, 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Awh[+]/Awh16 is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4bbg-C96, mamH.UAS

      (Singh et al., 2025)

      Awh[+]/Awh16 is a suppressor | partially of visible | adult stage phenotype of NDN.UAS.cUa, Scer\GAL4bbg-C96

      (Singh et al., 2025)

      Awh[+]/Awh16 is a suppressor of visible | dominant | adult stage phenotype of Nnd-3

      (Singh et al., 2025)
      Other
      Statement
      Reference

      Awh16, Df(3R)Delta-BX6 has visible | adult stage phenotype

      (Singh et al., 2025)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Awh[+]/Awh16 is a suppressor | partially of wing margin phenotype of Scer\GAL4bbg-C96, mamH.UAS

      (Singh et al., 2025)

      Awh[+]/Awh16 is a suppressor | partially of wing margin phenotype of NDN.UAS.cUa, Scer\GAL4bbg-C96

      (Singh et al., 2025)

      Awh[+]/Awh16 is a suppressor of wing margin phenotype of Nnd-3

      (Singh et al., 2025)
      Other
      Statement
      Reference

      Awh16, Df(3R)Delta-BX6 has wing vein phenotype

      (Singh et al., 2025)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Awh16
      (Singh et al., 2025, Preger-Ben Noon et al., 2016, Roignant et al., 2010)
      awh16
      (Komiyama and Luo, 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)