FlyBase Allele Report: Dmel\Chi[k04405]

(Ramain et al., 2000, Roch et al., 1998, Kolhekar et al., 1997, Morcillo et al., 1997, Morcillo and Dorsett, 1996, BDGP Project Members, 1994-1999)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

O18353

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Roch et al., 1998, Morcillo and Dorsett, 1996)

lethal - all die before end of larval stage

(Morcillo et al., 1997)

some die during larval stage

(Morcillo et al., 1997)

Phenotype Manifest In

Detailed Description

Statement

Reference

Lethality occurs during third instar larval or pupal stages. Mutants do not show any visible disc abnormalities.

(Roch et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Chi^k04405 is an enhancer of phenotype of ct^unspecified

(Morcillo and Dorsett, 1996)

Chi^k04405 is an enhancer of phenotype of Ubx^unspecified

(Morcillo and Dorsett, 1996)

Additional Comments

Genetic Interactions

Statement

Reference

Enhances the mutant phenotype of the gypsy insertion alleles of ct and Ubx.

(Morcillo and Dorsett, 1996)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Chi^E

(Ramain et al., 2000)

Comments

Complements Phm^k07623.

(Kolhekar et al., 1997)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

This allele was listed in the BDGP database as a lethal or sterile line during the period 1994-1999, but was discarded from the gene disruption project prior to the summary publication (FBrf0111489). Reasons for excluding lines from the collection described in FBrf0111489 include presence of more than one P insertion on the mutant chromosome, separation of lethality (or sterility) from the location of the insertion, and loss of lethality (or sterility) from the stock. Further information is available from http://www.fruitfly.org/bfd/ and from Dr. Spradling (spradling@mail1.ciwemb.edu).

Complements: eIF-5A⁰¹²⁹⁶. Complements: l(2)05006⁰⁵⁰⁰⁶. Complements: tsr^k03101. Complements: Adk2-60B^k04201. Complements: tsr^k05403. Complements: tsr^k05633. Complements: Phm^k07623.

(BDGP Project Members, 1994-1999)

Precise excisions of the P{lacW} insertion revert the lethal phenotype.

(Morcillo et al., 1997)

External Crossreferences and Linkouts ( 3 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AF010325

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

AAB62574

UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information

O18353

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

04405

(Kolhekar et al., 1997)

44/5

(Roch et al., 1998)

Chi¹

Chi^k04405

l(2)k04405^k04405

Name Synonyms

Secondary FlyBase IDs

FBal0061269

References (6)

Report Sections

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