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General Information
Symbol
Dmel\Ubxunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0049236
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
unspecified
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Heterozygotes show mild transformations of haltere to wing.

    Antpunspecified Ubxunspecified embryos show transformation of the mesothoracic, metathoracic and first abdominal segments towards the prothoracic segment, and have bilaterally symmetric regions of sclerotised cuticle in the mesothoracic and metathoracic segments.

    Dominant mutation. Ubxunspecified/Df(3R)P115 tissue in the posterior compartment of the mesothoracic legs shows transformation to the posterior compartment of the prothoracic leg in gynandromorphs.

    Homozygous larvae have four intracortical bands, one at each of the first four neuromeres in the central nervous system.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Suppressor of
    Statement
    Reference
    Phenotype Manifest In
    Enhanced by
    Statement
    Reference

    Ubxunspecified has phenotype, enhanceable by Chik04405

    Ubxunspecified has phenotype, enhanceable by zae(bx)

    Suppressed by
    Statement
    Reference

    Ubxunspecified has phenotype, suppressible by skd2

    Enhancer of
    Suppressor of
    Statement
    Reference
    Other
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    The severity of wing phenotypes caused by homozygous Asxxen-72-3 mutant clones is reduced in a heterozygous Ubxunspecified mutant background. For example, no necrotic or dual-lobed wings are observed. In addition, the percentage of wing blisters or folded/bent wings is reduced and fewer flies have crumpled wings. In some cases, ripples are associated with visible clones containing small cells, whereas other ripples are not associated with the presence of smaller cells.

    Scrunspecified, Antpunspecified, Ubxunspecified, abd-Aunspecified, Abd-Bunspecified mutants are profoundly affected in their development with abnormal or twisted dorsal closure.

    Expression of vgScer\UAS.cKa under the control of Scer\GAL4bi-md653 in a Ubxunspecified/+ background results in enhanced transformation of the haltere to wing.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    Comments
    Comments

    The sensitivity of the metanotal transformation of the Ubxunspecified/Ubxbx-34e genotype to chromosomal rearrangements has been studied in the presence and absence of za.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Name Synonyms
    Secondary FlyBase IDs
      References (15)