FlyBase Allele Report: Dmel\so[9]

General Information

Symbol

Dmel\so⁹

Species

D. melanogaster

Name

FlyBase ID

FBal0050549

Feature type

allele

Associated gene

Dmel\so

Associated Insertion(s)

P{?'A92}so⁹

Carried in Construct

Key Links

Allele class

loss of function allele

hypomorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Kenyon et al., 2005)

loss of function allele

(Cheyette et al., 1994)

Mutagen

P-element activity

(Cheyette et al., 1994)

Progenitor genotype

so⁷

(Cheyette et al., 1994)

Associated Insertion(s)

P{?'A92}so⁹

Cytology

Description

Partial excision of the P-element and deletion into exon 1a.

(Cheyette et al., 1994)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile | male (with so³)

(Fabrizio et al., 2003)

viable

(Kenyon et al., 2005, Cheyette et al., 1994)

viable (with so³)

(Fabrizio et al., 2003)

visible

(Cheyette et al., 1994)

Phenotype Manifest In

Bolwig organ

(Cheyette et al., 1994)

eye

(Kenyon et al., 2005, Cheyette et al., 1994)

eye disc & neuron

(Kenyon et al., 2005)

ocellus

(Kenyon et al., 2005)

visual primordium

(Cheyette et al., 1994)

Detailed Description

Statement

Reference

so⁹ flies have small eyes with reduced ocelli. At the larval stage, the eye field is reduced and neurogenesis arrests, first along the margins of the eye disc, and then in the centre.

(Kenyon et al., 2005)

so⁹/so³ adult males are viable and fertile, and have normal looking testes with no degenerating speramtocytes.

(Fabrizio et al., 2003)

Homozygotes have slightly reduced and roughened eyes. The optic lobe primordium of homozygotes is reduced in size and movement into the head cavity is arrested at an early stage so it fails to invaginate.

(Cheyette et al., 1994)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

Df(2L)eya¹⁰, so⁹/so³ has spermatocyte phenotype

(Fabrizio et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Significant levels of spermatocyte degeneration is seen in the testes of Df(2L)eya¹⁰ so⁹/so³ adults and pharate adults.

(Fabrizio et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

so⁹ is rescued by so^hs.PC

(Cheyette et al., 1994)

Comments

Mutant eye phenotype can be rescued by heat induced expression of so (repetitive heat shocks during third instar).

(Cheyette et al., 1994)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

SO⁹

(Kenyon et al., 2005)

so⁹

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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