FB2026_02 , released June 18, 2026
Allele: Dmel\ChATm7.4
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General Information
Symbol
Dmel\ChATm7.4
Species
D. melanogaster
Name
FlyBase ID
FBal0055185
Feature type
allele
Associated gene
Dmel\ChAT
Associated Insertion(s)
Carried in Construct
P{ChATm7.4}
Key Links
Transgenic product class
cDNA
(Kitamoto et al., 1992)
wild_type
(Kitamoto et al., 1992)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Kitamoto et al., 1992)
wild_type
(Kitamoto et al., 1992)
Mutagen
in vitro construct
(Kitamoto et al., 2000, Kitamoto and Salvaterra, 1995, Yasuyama et al., 1995, Kitamoto and Salvaterra, 1993, Kitamoto et al., 1992)
Progenitor genotype
Carried in construct
P{ChATm7.4}
Cytology
Description

Minigene composed of a 7.4kb fragment containing the common regulatory DNA for ChAT and VAChT fused to the wild-type ChAT cDNA.

(Kitamoto et al., 2000)

7.4kb of Cha 5' flanking sequences drive expression of a 2.4kb Cha cDNA, containing the entire protein coding sequence.

(Kitamoto et al., 1992)
Allele components
Component
Use(s)
Regulatory region(s)
ChAT
VAChT
Encoded product / tool
ChAT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In an otherwise null background, flies show normal optomotor and gustatory responses but reduced motor activity.

      (Yasuyama et al., 1995)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      ChATm7.4 is a non-suppressor of lethal phenotype of VAChT2/Df(3R)Cha5

      (Kitamoto et al., 2000)

      ChATm7.4 is a non-suppressor of lethal phenotype of Df(3R)Cha5/VAChT1

      (Kitamoto et al., 2000)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ChATm7.4
      Cham7.4
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0029093
      References (5)