FlyBase Allele Report: Dmel\βTub60D[sk]

General Information

Symbol

Dmel\βTub60D^sk

Species

D. melanogaster

Name

FlyBase ID

FBal0055392

Feature type

allele

Associated gene

Dmel\βTub60D

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

gamma ray

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Dettman et al., 2001)

Mutagen

gamma ray

(Dettman et al., 1996)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal phototaxis (with Df(2R)Px2)

(Dettman et al., 2001)

abnormal phototaxis | recessive

(Dettman et al., 2001)

flightless (with βTub60D⁵)

(Dettman et al., 1996)

lethal | larval stage | recessive

(Dettman et al., 1996)

lethal | pupal stage | recessive

(Dettman et al., 1996)

lethal - all die before end of larval stage | recessive

(Dettman et al., 2001)

some die during larval stage | recessive

(Dettman et al., 2001)

sterile (with βTub60D¹)

(Dettman et al., 1996)

sterile (with βTub60D⁴)

(Dettman et al., 1996)

sterile (with βTub60D^P126)

(Dettman et al., 1996)

viable (with βTub60D¹)

(Dettman et al., 1996)

viable (with βTub60D⁴)

(Dettman et al., 1996)

viable (with βTub60D⁵)

(Dettman et al., 1996)

viable (with βTub60D^P126)

(Dettman et al., 1996)

Phenotype Manifest In

Detailed Description

Statement

Reference

Lethality acts in the second larval instar. Overall morphology of Bolwig's organ and nerve are normal in mutant larvae. Wild type foraging larvae show strong tendency towards photonegativity in a "Darth Vader" light avoidance assay. Homozygous mutants are less photonegative and hemizygous mutants are photoneutral.

(Dettman et al., 2001)

Transheterozygotes with βTub60D⁵ are viable but flightless, transheterozygotes with βTub60D¹, βTub60D⁴ and βTub60D^P126 are viable but sterile.

(Dettman et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement