FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rhoUAS.cXa
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General Information
Symbol
Dmel\rhoUAS.cXa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Xiao
FlyBase ID
FBal0059756
Feature type
allele
Associated gene
Dmel\rho
Associated Insertion(s)
Carried in Construct
P{UAS-ve.(rho)X}
Also Known As
UAS-rho
Key Links
Transgenic product class
cDNA
(Xiao et al., 1996)
wild_type
(Xiao et al., 1996)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Xiao et al., 1996)
wild_type
(Xiao et al., 1996)
Mutagen
in vitro construct
(Xiao et al., 1996)
Progenitor genotype
Carried in construct
P{UAS-ve.(rho)X}
Cytology
Description

UASt regulatory sequences drive expression of a full-length rho cDNA.

(Xiao et al., 1996)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
rho
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of rhoScer\UAS.cXa driven by Scer\GAL4sim.P3.7 or by Scer\GAL4sli.PS does not affect the numbers of midline glial cells (MGs) at stage 12/0 or at stage 17. However when driven by Scer\GAL4sca-537.4 a higher number of MGs are seen.

      (Lanoue and Jacobs, 1999)

      Scer\GAL4prd.RG1-mediated expression causes ectopic dorsal median cells in alternating segments. Scer\GAL452B-mediated expression causes ectopic mesodermal cells in stage 14 embryos that migrate normally to lateral regions of the embryo.

      (Zhou et al., 1997)

      Scer\GAL4prd.RG1 mediated expression in wild type embryos causes altered denticle morphology; terminal regions of the denticles are slightly widened and squared off rather than being the normal tapered shape. Altered morphology is consistent with a transformation of terminal denticle structures to a more ventral structure.

      (Xiao et al., 1996)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      rhoUAS.cXa/Scer\GAL4sim.P3.7 partially rescues rho7M43

      (Xiao et al., 1996)
      Fails to rescue

      rhoUAS.cXa/Scer\GAL4sim.P3.7 fails to rescue rhoPΔ38

      (Lanoue and Jacobs, 1999)
      Comments

      The addition of rhoScer\UAS.cXa driven by Scer\GAL4sim.P3.7 to rhoPΔ38 embryos is not sufficient to rescue the loss of midline glial cell phenotype seen in these mutants.

      (Lanoue and Jacobs, 1999)

      Scer\GAL4sim.P3.7 mediated expression greatly rescues rho7M43 embryonic cuticle phenotype but not the CNS phenotype.

      (Xiao et al., 1996)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      rhoScer\UAS.cXa
      rhoUAS.cXa
      veScer\UAS.cXa
      (Zhou et al., 1997)
      veUAS.cXa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Xiao
      (Xiao et al., 1996)
      Secondary FlyBase IDs
        References (6)