Open Close
General Information
Symbol
Dmel\rhoUAS.cXa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Xiao
FlyBase ID
FBal0059756
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-rho
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a full-length rho cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of rhoScer\UAS.cXa driven by Scer\GAL4sim.P3.7 or by Scer\GAL4sli.PS does not affect the numbers of midline glial cells (MGs) at stage 12/0 or at stage 17. However when driven by Scer\GAL4sca-537.4 a higher number of MGs are seen.

Scer\GAL4prd.RG1-mediated expression causes ectopic dorsal median cells in alternating segments. Scer\GAL452B-mediated expression causes ectopic mesodermal cells in stage 14 embryos that migrate normally to lateral regions of the embryo.

Scer\GAL4prd.RG1 mediated expression in wild type embryos causes altered denticle morphology; terminal regions of the denticles are slightly widened and squared off rather than being the normal tapered shape. Altered morphology is consistent with a transformation of terminal denticle structures to a more ventral structure.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

The addition of rhoScer\UAS.cXa driven by Scer\GAL4sim.P3.7 to rhoPΔ38 embryos is not sufficient to rescue the loss of midline glial cell phenotype seen in these mutants.

Scer\GAL4sim.P3.7 mediated expression greatly rescues rho7M43 embryonic cuticle phenotype but not the CNS phenotype.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
rhoScer\UAS.cXa
rhoUAS.cXa
veScer\UAS.cXa
veUAS.cXa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Xiao
Secondary FlyBase IDs
    References (6)