FB2026_02 , released June 18, 2026
Allele: Dmel\oro2
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General Information
Symbol
Dmel\oro2
Species
D. melanogaster
Name
FlyBase ID
FBal0060966
Feature type
allele
Associated gene
oro
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Epps et al., 1997)
Mutagen
diepoxybutane
(Epps et al., 1997)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Approximately 50% of homozygous embryos have an abnormal cuticle pattern, with 10-15% of these embryos having a wg- or hh-like cuticle pattern.

      (Epps et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      oro2, ptc9 has viable phenotype

      (Epps et al., 1997)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      oro2/oro[+] is an enhancer of eye phenotype of hhbar3

      (Epps et al., 1997)

      oro2/oro[+] is an enhancer of ommatidium phenotype of hhbar3

      (Epps et al., 1997)

      oro2/oro[+] is an enhancer of eye phenotype of Bar1

      (Epps et al., 1997)

      oro2 is an enhancer of wing vein L3 phenotype of fu1

      (Epps et al., 1997)

      oro2 is an enhancer of wing vein L4 phenotype of fu1

      (Epps et al., 1997)

      oro2 is an enhancer of lateral ocellus phenotype of fu1

      (Epps et al., 1997)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dominant enhancer of the B1 and hhbar3 eye phenotypes. 81% of oro1 ptc9/oro2 flies are viable. Dominantly enhances the fu1 wing and ocellus phenotypes.

      (Epps et al., 1997)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      oro1

      (Epps et al., 1997)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Isolated in a screen for mutations affecting morphogenetic furrow progression during early eye development. oro1 is a stronger enhancer of the B1 eye phenotype than oro2.

      (Epps et al., 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      oro2
      Name Synonyms
      Secondary FlyBase IDs
        References (2)