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General Information
Symbol
Dmel\B1
Species
D. melanogaster
Name
FlyBase ID
FBal0000817
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
B
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

B-H1 but not B-H2 is duplicated in the Dp(1;1)B duplication associated with the B1 allele.

Insertion of a roo-element at cytological location 16A7-16A1.

Caused by aberration
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

B1 flies have reduced eye size.

Heterozygotes have a deep anterior nick in the adult eye.

All three pairs of legs are wild type in mutant flies. The antennae are normal.

B1 males that are also mutant at mle4 males have narrower eyes than their mle4/+ sibs.

Eye restricted to narrow vertical bar. Homozygous female fully viable. B1/+ female has about 360 facets and shows indentation terminating in horizontal fissure on anterior margin of eye, producing a kidney-shaped eye. B1/B1 and B1/+ completely separable from wild type; in some genetic backgrounds, B1/B1 overlaps B1/+ slightly. Classifiable in single dose in triploids by slight anterior nick in eye; is useful in the recognition of triploids.

RK1A. Dana\B-H1 sequences hybridized to the duplicated regions of B1, B2, BMR2 and BMR3.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

B1 has visible | dominant phenotype, enhanceable by br5/br[+]

B1 has visible | dominant phenotype, enhanceable by brnpr-3/br[+]

Suppressed by
Statement
Reference

B1 has visible | dominant phenotype, suppressible by br[+]/br2Bc-1

B1 has visible | dominant phenotype, suppressible by brrbp-5/br[+]

B1 has visible phenotype, suppressible by su(Bar)1

Enhancer of
Statement
Reference

B[+]/B1 is an enhancer of visible | dominant phenotype of L2

B1 is an enhancer of visible phenotype of dppd6/dppd12

Phenotype Manifest In
Enhanced by
Statement
Reference

B1 has eye phenotype, enhanceable by Lpt1

B1, ecd1 has eye phenotype, enhanceable by trr1

B1 has eye phenotype, enhanceable by br5/br[+]

B1 has eye phenotype, enhanceable by brnpr-3/br[+]

B1 has eye phenotype, enhanceable by oro1/oro[+]

B1 has eye phenotype, enhanceable by oro2/oro[+]

B1 has phenotype, enhanceable by Bg2

Suppressed by
Statement
Reference

B1 has eye phenotype, suppressible by trr+t12

B1 has eye phenotype, suppressible by br[+]/br2Bc-1

B1 has eye phenotype, suppressible by brrbp-5/br[+]

B1 has phenotype, suppressible | partially by su(Hw)2

B1 has ommatidium phenotype, suppressible by su(Bar)1

B1 has phenotype, suppressible by mb1

Enhancer of
Statement
Reference

B[+]/B1 is an enhancer of eye phenotype of L2

B[+]/B1 is an enhancer of eye phenotype of dppd-blk

B1 is an enhancer of antenna phenotype of dppd6/dppd12

B1 is an enhancer of tarsal segment phenotype of dppd6/dppd12

B1 is an enhancer of tibia phenotype of dppd6/dppd12

B1 is an enhancer of arista phenotype of dppd6/dppd12

B1 is an enhancer of femur phenotype of dppd6/dppd12

B1 is an enhancer of leg phenotype of dppd6/dppd12

B1 is an enhancer of male genitalia phenotype of dppd6/dppd12

B1 is an enhancer of ommatidium phenotype of dppd6/dppd12

B1 is an enhancer of phenotype of Bg2

Other
Additional Comments
Genetic Interactions
Statement
Reference

Lpt1/+ strongly enhances the reduced eye phenotype of B1/+ flies.

B1/+ ; L2/+ animals have a no eye phenotype.

In animals that are homozygous for ecd1 and are also B1 the addition of trr1 enhances the eye phenotype.

The severity of the leg defects seen in dppd6/dppd16 flies is enhanced by B1. There is an overall shortening in length along the proximal-distal axis of the leg and complete or partial fusion or even total loss of tarsal segments. The tibia and femur are deformed, showing shortening, bulging and disorganised bristle patterns. The coxa and trochanter are not so strongly affected. The sex comb of the prothoracic leg, when present, is always duplicated in these flies. The antenna phenotype of dppd6/dppd16 flies is enhanced by B1; the arista, 4th and 5th segments are completely absent and the 2nd and 3rd segments are widened and deformed and have defects in the bristle pattern. B1 ; dppd6/dppd16 flies completely lack ommatidia. All B1 ; dppd6/dppd16 males completely lack external genitalia.

The B1 eye phenotype is dominantly enhanced by oro1 and oro2. The eyes of oro1/+ ; B1/+ flies are approximately half the size of those of B1/+ flies.

Interacts with B1 to give small, glazed, almost facetless eyes.

su(B)1 is a recessive modifier of B1; it causes a great increase in the number of facets in the eyes of B1 males, and a slight increase in the number of facets in the eyes of homozygous B1 females.

mb1 is a recessive suppressor of B1; it modifies B1/B1 females to a phenotype resembling or less severe than B1/+ and modifies B1/+ females to almost resemble wild type. B1 males are modified to a phenotype resembling or less severe than Bi.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (1)
Stocks (99)
Notes on Origin
Discoverer

Selected as: Female.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (27)