FlyBase Allele Report: Scer\GAL4[337Y]

General Information

Symbol

Scer\GAL4^337Y

Species

S. cerevisiae

Name

FlyBase ID

FBal0063398

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}337Y

Carried in Construct

Also Known As

337, 337-GAL4

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Manseau et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{GawB}337Y

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 16 -- 17

organism | ubiquitous

(Manseau et al., 1997)

embryonic stage 16 -- adult stage

organism | ubiquitous

(Lorbeck et al., 2011)

Additional Information

Statement

Reference

Expressed in all tissues very late in embryonic development.

(Manseau et al., 1997)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased mortality during development, with Tip60^E431Q.UAS

(Pirooznia et al., 2012)

lethal, with Tip60^E431Q.UAS

(Pirooznia et al., 2012)

lethal, with Tip60^RNAi.Z.UAS

(Zhu et al., 2007)

lethal - all die before end of larval stage, with Hsc70-3^D231S.UAS

(Elefant and Palter, 1999)

lethal - all die before end of larval stage, with Hsc70-3^K97S.UAS

(Elefant and Palter, 1999)

lethal - all die before end of larval stage, with Hsc70-4^D206S.UAS

(Elefant and Palter, 1999)

lethal - all die before end of larval stage, with Hsc70-4^K71S.UAS

(Elefant and Palter, 1999)

lethal - all die before end of pupal stage, with Tip60^E431Q.UAS

(Lorbeck et al., 2011)

majority die during P-stage, with Hsap\APP^{695.UAS.Tag:MYC}

(Pirooznia et al., 2012)

majority die during third instar larval stage, with Tip60^E431Q.UAS

(Pirooznia et al., 2012)

partially lethal - majority die, with Hsap\APP^{695.UAS.Tag:MYC}

(Pirooznia et al., 2012)

partially lethal - majority die, with Tip60^UAS.cPa

(Pirooznia et al., 2012)

short lived, with Hsap\APP^{695.UAS.Tag:MYC}

(Pirooznia et al., 2012)

some die during larval stage, with Hsc70-3^D231S.UAS

(Elefant and Palter, 1999)

some die during larval stage, with Hsc70-3^K97S.UAS

(Elefant and Palter, 1999)

some die during larval stage, with Hsc70-4^D206S.UAS

(Elefant and Palter, 1999)

some die during larval stage, with Hsc70-4^K71S.UAS

(Elefant and Palter, 1999)

some die during pupal stage, with Tip60^E431Q.UAS

(Lorbeck et al., 2011)

viable, with Hsap\APP^{695ΔCT.UAS.Tag:MYC}

(Pirooznia et al., 2012)

viable, with Tip60^UAS.cLa

(Lorbeck et al., 2011)

visible | heat sensitive, with if^GOF.m8.UAS

(Baker et al., 2002)

visible | heat sensitive, with if^LOF.m8.UAS

(Baker et al., 2002)

visible | heat sensitive, with if^m8.UAS

(Baker et al., 2002)

Phenotype Manifest In

wing | heat sensitive, with if^GOF.m8.UAS

(Baker et al., 2002)

wing | heat sensitive, with if^LOF.m8.UAS

(Baker et al., 2002)

wing | heat sensitive, with if^m8.UAS

(Baker et al., 2002)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^337Y, Tip60^E431Q.UAS has increased mortality during development phenotype, enhanceable by Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^337Y

(Pirooznia et al., 2012)

Scer\GAL4^337Y, if^LOF.m8.UAS has visible | heat sensitive phenotype, enhanceable by mys[+]/mys^unspecified

(Baker et al., 2002)

Suppressed by

Statement

Reference

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^337Y has majority die during P-stage phenotype, suppressible | partially by Tip60^UAS.cPa, Scer\GAL4^337Y

(Pirooznia et al., 2012)

Scer\GAL4^337Y, if^GOF.m8.UAS has visible | heat sensitive phenotype, suppressible by mys[+]/mys^unspecified

(Baker et al., 2002)

NOT suppressed by

Statement

Reference

Scer\GAL4^337Y, Tip60^E431Q.UAS has lethal phenotype, non-suppressible by Hsap\APP^{695ΔCT.UAS.Tag:MYC}, Scer\GAL4^337Y

(Pirooznia et al., 2012)

Scer\GAL4^337Y, Tip60^E431Q.UAS has majority die during third instar larval stage phenotype, non-suppressible by Hsap\APP^{695ΔCT.UAS.Tag:MYC}, Scer\GAL4^337Y

(Pirooznia et al., 2012)

Scer\GAL4^337Y, Tip60^E431Q.UAS has lethal phenotype, non-suppressible by Hsap\APP^{695ΔCT.UAS.Tag:MYC}/Scer\GAL4^179Y

(Pirooznia et al., 2012)

Scer\GAL4^337Y, Tip60^E431Q.UAS has majority die during third instar larval stage phenotype, non-suppressible by Hsap\APP^{695ΔCT.UAS.Tag:MYC}/Scer\GAL4^179Y

(Pirooznia et al., 2012)

Scer\GAL4^337Y, Tip60^UAS.cPa has partially lethal - majority die phenotype, non-suppressible by Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^337Y

(Pirooznia et al., 2012)

Scer\GAL4^337Y, Tip60^UAS.cPa has partially lethal - majority die phenotype, non-suppressible by Hsap\APP^{695ΔCT.UAS.Tag:MYC}, Scer\GAL4^337Y

(Pirooznia et al., 2012)

Enhancer of

Statement

Reference

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^337Y is an enhancer of increased mortality during development phenotype of Scer\GAL4^337Y, Tip60^E431Q.UAS

(Pirooznia et al., 2012)

Suppressor of

Statement

Reference

Tip60^UAS.cPa, Scer\GAL4^337Y is a suppressor | partially of majority die during P-stage phenotype of Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^337Y

(Pirooznia et al., 2012)

NOT Suppressor of

Statement

Reference

Hsap\APP^{695ΔCT.UAS.Tag:MYC}, Scer\GAL4^337Y is a non-suppressor of lethal phenotype of Scer\GAL4^337Y, Tip60^E431Q.UAS

(Pirooznia et al., 2012)

Hsap\APP^{695ΔCT.UAS.Tag:MYC}, Scer\GAL4^337Y is a non-suppressor of majority die during third instar larval stage phenotype of Scer\GAL4^337Y, Tip60^E431Q.UAS

(Pirooznia et al., 2012)

Hsap\APP^{695.UAS.Tag:MYC}, Scer\GAL4^337Y is a non-suppressor of partially lethal - majority die phenotype of Scer\GAL4^337Y, Tip60^UAS.cPa

(Pirooznia et al., 2012)

Hsap\APP^{695ΔCT.UAS.Tag:MYC}, Scer\GAL4^337Y is a non-suppressor of partially lethal - majority die phenotype of Scer\GAL4^337Y, Tip60^UAS.cPa

(Pirooznia et al., 2012)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^337Y, if^LOF.m8.UAS has wing | heat sensitive phenotype, enhanceable by mys[+]/mys^unspecified

(Baker et al., 2002)

Suppressed by

Statement

Reference

Scer\GAL4^337Y, if^GOF.m8.UAS has wing | heat sensitive phenotype, suppressible by mys[+]/mys^unspecified

(Baker et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^337Y/Tip60^UAS.cLa rescues Tip60^E431Q.UAS

(Lorbeck et al., 2011)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

32119

w^*; P{GawB}337Y

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GAL4^337Y

Scer\GAL4^337Y

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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