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General Information
Symbol
Dmel\pnrD4.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0082344
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-pnrD4
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

pnrD4 is expressed under the control of UASt regulatory sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of pnrD4.UAS under the control of Scer\GAL4He.PZ or Scer\GAL4lz-gal4 leads to an increase in larval crystal cell numbers when compared to controls.

Expression of pnrD4.Scer\UAS under the control of Scer\GAL4ey.PH results in a small or no eye phenotype.

Expression of pnrD4.Scer\UAS under the control of Scer\GAL4ey.PH results in a dramatic reduction in the size of the eye disc and a complete loss of the eye.

Overexpression of pnrD4.Scer\UAS using Scer\GAL4pnr-MD237 leads to an excess of dorsocentral bristles and reduced viability.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

Scer\GAL4ey.PH, pnrD4.UAS has visible phenotype, enhanceable by L2/L[+]

Scer\GAL4bi-omb-Gal4, pnrD4.UAS has visible phenotype, enhanceable by L2/L[+]

Other
Phenotype Manifest In
Enhanced by
Statement
Reference

Scer\GAL4ey.PH, pnrD4.UAS has eye phenotype, enhanceable by L2/L[+]

Scer\GAL4bi-omb-Gal4, pnrD4.UAS has eye phenotype, enhanceable by L2/L[+]

Suppressed by
Other
Additional Comments
Genetic Interactions
Statement
Reference

Only 41% of L2/+ animals expressing pnrD4.Scer\UAS under the control of Scer\GAL4ey.PH eclose, and these animals have greatly reduced heads with no eyes, but normal antennae.

Flies expressing both pnrD4.Scer\UAS and Dl::NΔECN.Scer\UAS under the control of Scer\GAL4ey.PH show restored photoreceptor differentiation in the eye disc.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
pnrD4.Scer\UAS
pnrD4.UAS
Name Synonyms
Secondary FlyBase IDs
    References (8)