FlyBase Allele Report: Dmel\Csk[S017909]

General Information

Symbol

Dmel\Csk^S017909

Species

D. melanogaster

Name

FlyBase ID

FBal0082748

Feature type

allele

Associated gene

Dmel\Csk

Associated Insertion(s)

P{lacW}Csk^S017909

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

Nature of the Allele

Allele class

loss of function allele

(Read et al., 2004)

Mutagen

Delta2-3 transposase

(Deak et al., 1997)

P-element activity

(Szeged Stock Center, 1998-)

Progenitor genotype

Associated Insertion(s)

P{lacW}Csk^S017909

Cytology

Description

Plasmid rescue indicates that P{lacW}Csk^S017909 is inserted in Csk.

(Samakovlis, 2007.10.7)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Samakovlis, 2007.10.7)

lethal (with Df(3R)T-61)

(Deak et al., 1997)

lethal | recessive

(Read et al., 2004, Szeged Stock Center, 1998-)

lethal - all die before end of P-stage | recessive

(Deak et al., 1997)

some die during pharate adult stage | recessive

(Deak et al., 1997)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Csk^S017909/Csk[+] is an enhancer of abnormal neuroanatomy phenotype of Ppt1^UAS.cKa, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Phenotype Manifest In

Enhancer of

Statement

Reference

Csk^S017909/Csk[+] is an enhancer of eye phenotype of Ppt1^UAS.cKa, Scer\GAL4^GMR.PF

(Saja et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

A Csk^S017909/+ background enhances the visual system degeneration seen in Scer\GAL4^GMR.PF, Ppt1^Scer\UAS.cKa flies.

(Saja et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Csk^j1D8

(Read et al., 2004)

Rescued by

Csk^S017909 is rescued by Csk^hs.PR

(Read et al., 2004)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Lethality to due insertion P{lacW}Csk^S017909 is separable from lethality and tracheal phenotypes due to kkv^S017909.

(Samakovlis, 2007.10.7)

Separable from: kkv^S017909.

(Samakovlis, 2007.10.7)

Comments

Lethality is revertable on excision of the P{lacW}.

(Read et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

179/9

(Deak et al., 1997)

Csk^S017909

(O'Reilly et al., 2006)

S017909

(Read et al., 2004)

dCsk^S017909

(Read et al., 2004)

l(3)S017909^S017909

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close