FlyBase Allele Report: Dmel\aop[EP598]

General Information

Symbol

Dmel\aop^EP598

Species

D. melanogaster

Name

FlyBase ID

FBal0089473

Feature type

allele

Associated gene

Dmel\aop

Associated Insertion(s)

P{EP}aop^EP598

Carried in Construct

Also Known As

EP(2)0598

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Rorth et al., 1998)

Progenitor genotype

Associated Insertion(s)

P{EP}aop^EP598

Cytology

Description

P{EP} insertion at -98bp relative to the start of the transcription unit.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:2,178,785..2,178,792 [-]

(Kim et al., 2010, Weber et al., 2008, Levine et al., 2007, Singh et al., 2005, van Swinderen and Greenspan, 2005, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000, Warrick et al., 1999, Rorth et al., 1998)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

visible | dominant, with Scer\GAL4^bi-omb-Gal4

(Rorth et al., 1998)

Phenotype Manifest In

adult abdomen & trichogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

scutellar bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

scutellar bristle | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

tormogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

tormogen cell | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

trichogen cell | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

wing, with Scer\GAL4^bi-omb-Gal4

(Rorth et al., 1998)

wing vein, with Scer\GAL4^bi-omb-Gal4

(Rorth et al., 1998)

wing vein, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

Detailed Description

Statement

Reference

Flies expressing aop^EP598 under the control of Scer\GAL4^hs.2sev have wild-type eyes. Flies expressing aop^EP598 under the control of Scer\GAL4^en-e16E have incomplete wing venation.

(Tseng and Hariharan, 2002)

Expression of aop^EP598 under the control of Scer\GAL4^sca-537.4 results in too many or too few scutellar macrochaetae. Sensory organs with no socket and one shaft, one socket and two shafts and two sockets and one shaft are seen. On the abdomen short shaft morphology is seen.

(Abdelilah-Seyfried et al., 2000)

Expression of aop^EP598 under the control of Scer\GAL4^bi-omb-Gal4 produces wings of reduced size with mild vein pattern defects.

(Rorth et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^sca-537.4, aop^EP598 has visible phenotype, non-enhanceable by H[+]/H^E21

(Abdelilah-Seyfried et al., 2000)

Scer\GAL4^sca-537.4, aop^EP598 has visible phenotype, non-enhanceable by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

NOT suppressed by

Statement

Reference

Scer\GAL4^sca-537.4, aop^EP598 has visible phenotype, non-suppressible by H[+]/H^E21

(Abdelilah-Seyfried et al., 2000)

Scer\GAL4^sca-537.4, aop^EP598 has visible phenotype, non-suppressible by N[+]/N^55e11

(Abdelilah-Seyfried et al., 2000)

Enhancer of

Statement

Reference

aop^EP598/Scer\GAL4^ey.PH is an enhancer of visible | dominant phenotype of L²

(Singh et al., 2005)

Suppressor of

Statement

Reference

aop^EP598 is a suppressor of visible phenotype of Dcp-1^UAS.cKa, Scer\GAL4^GMR.PF

(Kim et al., 2010)

aop^EP598/Scer\GAL4^hs.2sev is a suppressor | partially of abnormal planar polarity phenotype of Scer\GAL4^hs.2sev, pnt^P2.UAS

(Weber et al., 2008)

aop^EP598/aop[+] is a suppressor of uncoordinated | dominant | heat sensitive phenotype of Syx1A^3-69

(van Swinderen and Greenspan, 2005)

Other

Statement

Reference

L², Scer\GAL4^ey.PH, aop^EP598 has lethal | dominant | pupal stage phenotype

(Singh et al., 2005)

Phenotype Manifest In

Enhancer of

Statement

Reference

aop^EP598/Scer\GAL4^ey.PH is an enhancer of eye phenotype of L²

(Singh et al., 2005)

NOT Enhancer of

Statement

Reference

aop^EP598/Scer\GAL4^sca-537.4 is a non-enhancer of phenotype of N^55e11

(Abdelilah-Seyfried et al., 2000)

aop^EP598/Scer\GAL4^sca-537.4 is a non-enhancer of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

Suppressor of

Statement

Reference

aop^EP598 is a suppressor of eye phenotype of Dcp-1^UAS.cKa, Scer\GAL4^GMR.PF

(Kim et al., 2010)

aop^EP598/Scer\GAL4^hs.2sev is a suppressor | partially of ommatidium phenotype of Scer\GAL4^hs.2sev, pnt^P2.UAS

(Weber et al., 2008)

NOT Suppressor of

Statement

Reference

aop^EP598/Scer\GAL4^sca-537.4 is a non-suppressor of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

aop^EP598 suppresses the rough eye phenotype seen when Dcp-1^Scer\UAS.cKa (insertion line P{UAS-Dcp-1.K}19-2) is expressed under the control of Scer\GAL4^GMR.PF.

(Kim et al., 2010)

Co-expression of aop^EP598 partially suppresses the symmetrical ommatidia phenotype caused by expression of pnt^P2.Scer\UAS under the control of Scer\GAL4^hs.2sev.

(Weber et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

EP(2)0598

(Abdelilah-Seyfried et al., 2000)

aop^EP598

Name Synonyms

Secondary FlyBase IDs

References (10)

Report Sections

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