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General Information
Symbol
Dmel\cora8
Species
D. melanogaster
Name
FlyBase ID
FBal0097014
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
cor8
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

A19236841C

Amino acid change:

D368A | cora-PA; D368A | cora-PB; D368A | cora-PC; D368A | cora-PE; D368A | cora-PF; D368A | cora-PG

Reported amino acid change:

D368A

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: D368A.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygotes die as embryos or larvae. Homozygous embryos have a faint cuticle. Adult escapers are produced. cora8/cora14 adults have eye defects; part of the anterior equatorial region of the eye is replaced by head cuticle and associated bristles, and in other parts of the eye the ommatidia are irregular in size and shape and bristles are misplaced.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement
Reference

cora8 is a suppressor of visible | dominant phenotype of EgfrE1

Phenotype Manifest In
Suppressor of
Statement
Reference

cora8 is a suppressor of eye phenotype of EgfrE1

Additional Comments
Genetic Interactions
Statement
Reference

Slightly suppresses the rough eye phenotype of EgfrE1/+ heterozygotes.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
Partially rescued by
Comments

cora8 animals rescued by expression of cora1-383.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4T80 are fertile.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)