FlyBase Allele Report: Dmel\Nipped-B[359.1]

General Information

Symbol

Dmel\Nipped-B^359.1

Species

D. melanogaster

Name

FlyBase ID

FBal0098360

Feature type

allele

Associated gene

Dmel\Nipped-B

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

loss of function allele

Mutagen

gamma ray

Nature of the Allele

Allele class

loss of function allele

(Rollins et al., 1999)

Mutagen

gamma ray

(Rollins et al., 1999)

Progenitor genotype

Caused by aberration

T(2;3)Nipped-B^359.1

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of larval stage | recessive

(Rollins et al., 1999)

some die during larval stage | recessive

(Rollins et al., 1999)

visible | adult stage | female

(Wu et al., 2015)

Phenotype Manifest In

synaptonemal complex

(Gause et al., 2008)

wing blade | female

(Wu et al., 2015)

Detailed Description

Statement

Reference

Nipped-B^359.1/+ adult females have smaller wings compared to wild-type.

(Wu et al., 2015)

Chromosome cores and the synaptonemal complex fragment in germarial region 3 or stage 2 oocytes in Nipped-B^359.1 heterozygotes, which is substantially earlier than in wild type.

Nipped-B^359.1 heterozygotes do not show meiotic chromosome segregation defects.

(Gause et al., 2008)

Recessive lethality acts at the L2-L3 molt.

(Rollins et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Nipped-B^359.1, ct^2s has visible | dominant phenotype

(Rollins et al., 1999)

Phenotype Manifest In

Enhancer of

Statement

Reference

Nipped-B[+]/Nipped-B^359.1 is an enhancer of wing phenotype of ct^L32, su(Hw)^e2

(Rollins et al., 1999)

NOT Enhancer of

Statement

Reference

Nipped-B^359.1 is a non-enhancer of phenotype of mam^g2.1

(Rollins et al., 1999)

Nipped-B^359.1 is a non-enhancer of phenotype of vg¹

(Rollins et al., 1999)

Nipped-B^359.1 is a non-enhancer of phenotype of ct^53d

(Rollins et al., 1999)

Nipped-B^359.1 is a non-enhancer of phenotype of Chi^e5.5

(Rollins et al., 1999)

Other

Statement

Reference

Nipped-B^359.1, ct^2s has wing phenotype

(Rollins et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Dominantly enhances the cut wing phenotype of ct^L32, su(Hw)^e2.

(Rollins et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Nipped-B⁰²⁰⁴⁷

(Rollins et al., 1999)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Nipped-B^359.1

(Gause et al., 2008)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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