FlyBase Allele Report: Dmel\Kap-α3[S033513]

General Information

Symbol

Dmel\Kap-α3^S033513

Species

D. melanogaster

Name

FlyBase ID

FBal0100114

Feature type

allele

Associated gene

Dmel\Kap-α3

Associated Insertion(s)

P{lacW}Kap-α3^S033513

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Deak et al., 1997)

P-element activity

(Szeged Stock Center, 1998-)

Progenitor genotype

Associated Insertion(s)

P{lacW}Kap-α3^S033513

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:9,577,357..9,579,714

(Mathe et al., 2000, Szeged Stock Center, 1998-, Deak et al., 1997)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(Mason et al., 2003)

viable

(Mason et al., 2003)

Phenotype Manifest In

Detailed Description

Statement

Reference

Kap-α3^S033513/Kap-α3^D93 flies have normal eyes.

(Mason et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Kap-α3^S033513 is an enhancer of visible | adult stage phenotype of N¹

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of visible | adult stage phenotype of N^nd-3

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of visible | adult stage phenotype of Delta^5F

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of visible | adult stage phenotype of Ser^Bd-3

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of visible | adult stage | male phenotype of dx¹⁵²

(Sachan et al., 2013)

Suppressor of

Statement

Reference

Kap-α3^S033513 is a suppressor of visible | adult stage phenotype of N^Ax-16

(Sachan et al., 2013)

Phenotype Manifest In

Enhancer of

Statement

Reference

Kap-α3^S033513 is an enhancer of wing margin phenotype of N¹

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of wing vein | male phenotype of dx¹⁵²

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of wing margin phenotype of N^nd-3

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of wing vein phenotype of Delta^5F

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of wing blade phenotype of Ser^Bd-3

(Sachan et al., 2013)

Kap-α3^S033513 is an enhancer of wing margin phenotype of Ser^Bd-3

(Sachan et al., 2013)

Suppressor of

Statement

Reference

Kap-α3^S033513 is a suppressor of wing vein L5 phenotype of N^Ax-16

(Sachan et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

The wing margin notching phenotype observed in some N¹ heterozygous females and in N^nd-3 hemizygous males, the wing vein deltas and thickening observed in Dl^5F heterozygotes as well as the large nicks in the anterior wing margin seen in Ser^Bd-3 heterozygous flies are each exacerbated by combination with a single copy of the Kap-α3^S033513 allele.

The shortened longitudinal L5 phenotype characteristic for N^Ax-16 heterozygous females is suppressed by combination with a single copy of the Kap-α3^S033513 allele.

The wing vein deltas and extra vein material observed in dx¹⁵² hemizygous adult males is exacerbated by combination with a single copy of the Kap-α3^S033513 allele. No wing defects are observed in adult females double heterozygote for dx¹⁵² and Kap-α3^S033513.

(Sachan et al., 2013)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Kap-α3^S033513 is rescued by Kap-α3^+t9

(Mathe et al., 2000)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Separable from: l(3)S033513^S033513.

(Mason et al., 2003)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

0335/13

(Deak et al., 1997)

Kap-α3^S033513

imp α3^1(R59)

(Sachan et al., 2013)

imp-α3¹

(Mathe et al., 2000)

importin α3¹

(Mason et al., 2003)

karyopherin-α3^S033513

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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