FlyBase Allele Report: Dmel\lqf[ARI]

General Information

Symbol

Dmel\lqf^ARI

Species

D. melanogaster

Name

FlyBase ID

FBal0104485

Feature type

allele

Associated gene

Dmel\lqf

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

X ray

Nature of the Allele

Allele class

Mutagen

X ray

(Cadavid et al., 2000)

Progenitor genotype

Cytology

Description

Small deletion.

(Cadavid et al., 2000)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Cadavid et al., 2000)

lethal - all die during embryonic stage (with lqf^L71)

(Xie et al., 2012)

some die during embryonic stage (with lqf^L71)

(Xie et al., 2012)

Phenotype Manifest In

dorsal vessel wall cell | increased number

(Tian et al., 2004)

eye photoreceptor cell | somatic clone

(Overstreet et al., 2004)

mesothoracic tergum & chaeta | supernumerary

(Tian et al., 2004)

Detailed Description

Statement

Reference

Photoreceptor cells are absent from the centers but not the borders of lqf^ARI homozygous somatic clones in the eye disc.

(Overstreet et al., 2004)

Homozygous embryos have an excess of cardioblasts; 200 +/- 41 cardioblasts develop in homozygotes compared to 104 +/- 7 cardioblasts in wild-type embryos. The cardioblasts are arranged in three to four poorly organised rows in the mutant embryos (in wild-type embryos they form two cell rows). The number of pericardial cells is relatively normal, although their organisation is slightly disrupted. When raised at 18^oC, 10% of mutant embryos show the excess cardioblast phenotype. 2.5% of heterozygotes have an extra notal bristle.

(Tian et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

lqf[+]/lqf^ARI is an enhancer of visible | dominant phenotype of Delta³

(Tian et al., 2004)

Other

Statement

Reference

aux^K47/aux^L7, lqf^ARI has visible phenotype

(Eun et al., 2007)

Phenotype Manifest In

Enhanced by

Statement

Reference

lqf^ARI has dorsal vessel wall cell | increased number phenotype, enhanceable by neur[+]/neur¹

(Tian et al., 2004)

lqf^ARI has mesothoracic tergum & chaeta | supernumerary phenotype, enhanceable by N[+]/N^55e11

(Tian et al., 2004)

lqf^ARI has dorsal vessel wall cell | increased number phenotype, enhanceable by Delta³/Dl[+]

(Tian et al., 2004)

Enhancer of

Statement

Reference

lqf[+]/lqf^ARI is an enhancer of posterior crossvein phenotype of Delta³

(Tian et al., 2004)

lqf[+]/lqf^ARI is an enhancer of wing vein L2 | distal phenotype of Delta³

(Tian et al., 2004)

lqf[+]/lqf^ARI is an enhancer of wing vein L2 phenotype of Delta³

(Tian et al., 2004)

lqf[+]/lqf^ARI is an enhancer of wing vein L4 phenotype of Delta³

(Tian et al., 2004)

lqf[+]/lqf^ARI is an enhancer of wing vein L5 | distal phenotype of Delta³

(Tian et al., 2004)

lqf[+]/lqf^ARI is an enhancer of dorsal vessel wall cell | increased number phenotype of N^l1N-ts1

(Tian et al., 2004)

lqf^ARI is an enhancer of phenotype of faf^unspecified

(Cadavid et al., 2000)

Other

Statement

Reference

aux^K47/aux^L7, lqf^ARI has wing phenotype

(Eun et al., 2007)

Additional Comments

Genetic Interactions

Statement

Reference

Heterozygosity for one of Dl³ or neur¹ increases the frequency of lqf^ARI embryos that show an excess cardioblast phenotype at 18^oC. The weak excess cardioblast phenotype seen in N^l1N-ts1 embryos raised at 30^oC is dominantly enhanced by lqf^ARI. lqf^ARI dominantly enhances the expressivity and penetrance of all Dl³/+ wing vein phenotypes. 40% of N^55e11 ; lqf^ARI double heterozygotes have extra notal bristles.

(Tian et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

lqf^L71/lqf^ARI is rescued by lqf^FL.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^ΔCBM.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^ΔDPW.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^ΔNPF.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^{ΔCBM.ΔDPW1.GFP}

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^ENTH.TD.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is rescued by lqf^{ENTH.FTVF.RDAA.GFP}

(Xie et al., 2012)

lqf^ARI is rescued by lqf^{ENTH.ro.Tag:FLAG}

(Overstreet et al., 2003)

Partially rescued by

lqf^L71/lqf^ARI is partially rescued by lqf^ΔENTH.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^ΔUIM.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^ΔUIM2.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^{UIM1.EA.ΔUIM2.GFP}

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^UIM1.EA.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^{ΔCBM.ΔDPW.GFP}

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^4xNPF.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is partially rescued by lqf^ENTH.RA.GFP

(Xie et al., 2012)

Not rescued by

lqf^L71/lqf^ARI is not rescued by lqf^ENTH.UIM.GFP

(Xie et al., 2012)

lqf^L71/lqf^ARI is not rescued by lqf^{ENTH.RWRK.AAAA.GFP}

(Xie et al., 2012)

Comments

lqf^ARI/lqf^L71 animals carrying lqf^{ΔENTH.T:Avic\GFP} are semi-viable and have a slight rough eye phenotype.

lqf^ARI/lqf^L71 animals carrying lqf^{ΔUIM.T:Avic\GFP} die as pupae.

lqf^{ΔUIM2.T:Avic\GFP} rescues the lethality of lqf^ARI/lqf^L71 animals and the resulting adults are almost wild type (97 +/- 3% of facets in the eye are normal).

lqf^ARI/lqf^L71 animals carrying lqf^{UIM1.EA.ΔUIM2.T:Avic\GFP} die as pupae.

lqf^{UIM1.EA.T:Avic\GFP} rescues the lethality of lqf^ARI/lqf^L71 animals and the resulting adults are almost wild type (68 +/- 12% of facets in the eye are normal).

lqf^{ΔCBM.ΔDPW.T:Avic\GFP} rescues the lethality of lqf^ARI/lqf^L71 animals and the resulting adults are almost wild type (92 +/- 2% of facets in the eye are normal).

lqf^ARI/lqf^L71 animals carrying lqf^{4xNPF.T:Avic\GFP} are semi-viable and have slight eye defects.

lqf^{ENTH.RA.T:Avic\GFP} rescues the lethality of lqf^ARI/lqf^L71 animals and the resulting adults are almost wild type (64 +/- 14% of facets in the eye are normal).

(Xie et al., 2012)

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

25106

w^*; lqf^ARI/TM6B, Tb¹

Notes on Origin

Discoverer

Selected as: an enhancer of the faf mutant phenotype.

(Cadavid et al., 2000)

Comments

Allelic series based on viability: lqf^FDD9 < lqf^bE248 < lqf^S011027 < lqf^BT < lqf^ARI = lqf^L895 = lqf^L71.

(Overstreet et al., 2003)

Allelic series of phenotypic severity: lqf^ARI >= lqf^AG > lqf^bE25 > lqf^bE248 > lqf^S011027.

(Tian et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

lqf^ARI

(Troost et al., 2023, Xie et al., 2012, Banks et al., 2011, Csikós et al., 2009, Eun et al., 2007, Wang and Struhl, 2004)

Name Synonyms

Secondary FlyBase IDs

References (10)

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