FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\slmbP245
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General Information
Symbol
Dmel\slmbP245
Species
D. melanogaster
Name
FlyBase ID
FBal0117352
Feature type
allele
Associated gene
Dmel\slmb
Associated Insertion(s)
P{lacW}slmbP245
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Miletich and Limbourg-Bouchon, 2000)
Mutagen
P-element activity
(Miletich and Limbourg-Bouchon, 2000)
Progenitor genotype
Associated Insertion(s)
P{lacW}slmbP245
Cytology
Description

The P{lacW} insertion is just after the second putative ATG (out of three present in the first four codons).

(Miletich and Limbourg-Bouchon, 2000)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When slmbP245 somatic clones are induced, a fraction of the ommatidia are replaced by dorsal head cuticle and sometimes bulging of the eye occurs.

      (Miletich and Limbourg-Bouchon, 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Mmus\Cul1UAS.cHa, Scer\GAL4Bx-MS1096, slmbP245 has wing phenotype, suppressible by E2f107172

      (Heriche et al., 2003)
      Enhancer of
      Statement
      Reference

      slmbP245 is an enhancer of wing phenotype of Mmus\Cul1UAS.cHa, Scer\GAL4Bx-MS1096

      (Heriche et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      A slmbP245 background enhances the small wing phenotype found in Mmus\Cul1Scer\UAS.cHa/Scer\GAL4Bx-MS1096 over-expression mutants. The presence of E2f107172 as well as slmbP245 reverses the enhancement of Mmus\Cul1Scer\UAS.cHa/Scer\GAL4Bx-MS1096 by a slmbP245 background.

      (Heriche et al., 2003)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      slmbP245
      (Heriche et al., 2003)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)