FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pimUAS.Tag:MYC
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General Information
Symbol
Dmel\pimUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0118074
Feature type
allele
Associated gene
Dmel\pim
Associated Insertion(s)
Carried in Construct
P{UAS-pim-myc}
Also Known As
UAS-pim-myc
Key Links
Transgenic product class
wild_type
(Leismann et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Leismann et al., 2000)
Mutagen
in vitro construct
(Leismann et al., 2000)
Progenitor genotype
Carried in construct
P{UAS-pim-myc}
Cytology
Description

UAS sequences drive expression of pim.

(Leismann et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
pim
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of pimScer\UAS.T:Hsap\MYC under the control of Scer\GAL4GMR.PF results in a rough eye phenotype.

      (Heeger et al., 2005)

      When driven by Scer\GAL4nos.bcd3'UTR.T:Scer\GCN4, pimScer\UAS.T:Hsap\MYC has no effect on sister chromatid separation when one copy of the P{UAS-pim-myc} transgene is present. Inhibition of sister chromatid separation is seen when two copies are present.

      (Leismann et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      NOT Enhanced by
      Statement
      Reference

      Scer\GAL4GMR.PF, pimUAS.Tag:MYC has visible phenotype, non-enhanceable by Df(3R)G1

      (Heeger et al., 2005)

      Scer\GAL4GMR.PF, pimUAS.Tag:MYC has visible phenotype, non-enhanceable by Df(3R)dsx11

      (Heeger et al., 2005)

      Scer\GAL4GMR.PF, pimUAS.Tag:MYC has visible phenotype, non-enhanceable by Df(3R)dsx27

      (Heeger et al., 2005)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The addition of one copy of P{UAS-pim-myc} to a fzy mutant does produce an inhibition of sister chromatid separation, normally only seen with two copies of P{UAS-pim-myc}.

      (Leismann et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pimScer\UAS.T:Hsap\MYC
      pimUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (4)