FlyBase Allele Report: Dmel\shn[EP2359]

General Information

Symbol

Dmel\shn^EP2359

Species

D. melanogaster

Name

FlyBase ID

FBal0119639

Feature type

allele

Associated gene

Dmel\shn

Associated Insertion(s)

P{EP}shn^EP2359

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}shn^EP2359

Cytology

Description

P{EP} insertion.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:11,173,730..11,173,730 [+]

(Bejarano et al., 2008, Pena-Rangel et al., 2002, Tseng and Hariharan, 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^hs.2sev

(Tseng and Hariharan, 2002)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

eye, with Scer\GAL4^hs.2sev

(Tseng and Hariharan, 2002)

ommatidium, with Scer\GAL4^hs.2sev

(Tseng and Hariharan, 2002)

scutellar bristle, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

wing vein, with Scer\GAL4^en-e16E

(Tseng and Hariharan, 2002)

Detailed Description

Statement

Reference

Expression of shn^EP2359 under the control of Scer\GAL4^ey.PH results in eyes that are strongly reduced in size. Flies expressing shn^EP2359 under the control of Scer\GAL4^hs.2sev have rough eyes. Flies expressing shn^EP2359 under the control of Scer\GAL4^en-e16E have wing venation defects.

(Tseng and Hariharan, 2002)

Expression of shn^EP2359 under the control of Scer\GAL4^sca-537.4 results in the loss of a few scutellar macrochaetae.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^ey.PH, shn^EP2359 has visible phenotype, suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

shn^EP2359/Scer\GAL4^pnr-MD237 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Suppressor of

Statement

Reference

Scer\GAL4^ap-md544/shn^EP2359 is a suppressor of visible phenotype of Bx¹

(Bejarano et al., 2008)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^ey.PH, shn^EP2359 has eye phenotype, suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

shn^EP2359/Scer\GAL4^pnr-MD237 is an enhancer of chaeta phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Suppressor of

Statement

Reference

Scer\GAL4^ap-md544/shn^EP2359 is a suppressor of wing margin phenotype of Bx¹

(Bejarano et al., 2008)

Other

Statement

Reference

Scer\GAL4^pnr-MD237, pnr^MD237, shn^EP2359 has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, pnr^MD237, shn^EP2359 has microchaeta & adult head phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+], shn^EP2359 has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+], shn^EP2359 has microchaeta & adult head phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing shn^EP2359 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and extra microchaetae around the ocelli.

(Pena-Rangel et al., 2002)

Co-expression of CycE^Scer\UAS.cLa suppresses the small eye phenotype caused by expression of shn^EP2359 under the control of Scer\GAL4^ey.PH.

(Tseng and Hariharan, 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

BEST:SD06302^EP2359

EP(2)2359

(Abdelilah-Seyfried et al., 2000)

EP2359^EP2359

shn^EP2359

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

Open Close