FlyBase Allele Report: Dmel\Tlk[EP1408]

General Information

Symbol

Dmel\Tlk^EP1408

Species

D. melanogaster

Name

FlyBase ID

FBal0119704

Feature type

allele

Associated gene

Dmel\Tlk

Associated Insertion(s)

P{EP}Tlk^EP1408

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}Tlk^EP1408

Cytology

Description

P{EP} insertion within EST GH17330. The P{EP} element is in antisense orientation relative to the transcription unit.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:3,749,021..3,749,021 [+]

(Zhu et al., 2005, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

tormogen cell | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

trichogen cell | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Detailed Description

Statement

Reference

Expression of BEST:GH17330^EP1408 under the control of Scer\GAL4^sca-537.4 results in sensory organs with two sockets and two shafts.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Scer\GAL4^sca-537.4, Tlk^EP1408 has visible phenotype, non-enhanceable by H^E21

(Abdelilah-Seyfried et al., 2000)

Scer\GAL4^sca-537.4, Tlk^EP1408 has visible phenotype, non-enhanceable by N^55e11

(Abdelilah-Seyfried et al., 2000)

NOT suppressed by

Statement

Reference

Scer\GAL4^sca-537.4, Tlk^EP1408 has visible phenotype, non-suppressible by H^E21

(Abdelilah-Seyfried et al., 2000)

Scer\GAL4^sca-537.4, Tlk^EP1408 has visible phenotype, non-suppressible by N^55e11

(Abdelilah-Seyfried et al., 2000)

Enhancer of

Statement

Reference

Tlk^EP1408, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Rac1^N17.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

Tlk^EP1408, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Cdc42^L89.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

Scer\GAL4^pnr-MD237/Tlk^EP1408 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

NOT Enhancer of

Statement

Reference

Scer\GAL4^GMR.PF/Tlk^EP1408 is a non-enhancer of visible phenotype of Scer\GAL4^GMR.PF, btl::Egfr^λ.UAS

(Zhu et al., 2005)

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/Tlk^EP1408 is a suppressor of visible phenotype of Scer\GAL4^GMR.PF, btl^λ.UAS, stumps^UAS.Tag:FLAG

(Zhu et al., 2005)

Tlk^EP1408, Scer\GAL4^GMR.PF is a suppressor | partially of visible phenotype of Pvr^λ.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

NOT Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/Tlk^EP1408 is a non-suppressor of visible phenotype of Scer\GAL4^GMR.PF, btl::Egfr^λ.UAS

(Zhu et al., 2005)

Other

Statement

Reference

Scer\GAL4^pnr-MD237, Tlk^EP1408, pnr^MD237/pnr[+] has abnormal planar polarity phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, Tlk^EP1408, pnr^MD237 has abnormal planar polarity phenotype

(Pena-Rangel et al., 2002)

Phenotype Manifest In

Enhancer of

Statement

Reference

Scer\GAL4^pnr-MD237/Tlk^EP1408 is an enhancer of chaeta phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Scer\GAL4^sca-537.4/Tlk^EP1408 is an enhancer of phenotype of N^55e11

(Abdelilah-Seyfried et al., 2000)

NOT Enhancer of

Statement

Reference

Scer\GAL4^GMR.PF/Tlk^EP1408 is a non-enhancer of eye phenotype of Scer\GAL4^GMR.PF, btl::Egfr^λ.UAS

(Zhu et al., 2005)

Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/Tlk^EP1408 is a suppressor of eye phenotype of Scer\GAL4^GMR.PF, btl^λ.UAS, stumps^UAS.Tag:FLAG

(Zhu et al., 2005)

Tlk^EP1408, Scer\GAL4^GMR.PF is a suppressor | partially of eye phenotype of Pvr^λ.UAS, Scer\GAL4^GMR.PF

(Zhu et al., 2005)

Scer\GAL4^sca-537.4/Tlk^EP1408 is a suppressor of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

NOT Suppressor of

Statement

Reference

Scer\GAL4^GMR.PF/Tlk^EP1408 is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PF, btl::Egfr^λ.UAS

(Zhu et al., 2005)

Other

Statement

Reference

Scer\GAL4^pnr-MD237, Tlk^EP1408, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, Tlk^EP1408, pnr^MD237/pnr[+] has microchaeta phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, Tlk^EP1408, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, Tlk^EP1408, pnr^MD237 has microchaeta phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing BEST:GH17330^EP1408 under the control of Scer\GAL4^pnr-MD237 have a deformed scutellum and microchaetae without polarity.

(Pena-Rangel et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

BEST:GH17330^EP1408

EP(X)1408

(Abdelilah-Seyfried et al., 2000)

EP1408^EP1408

Tlk^EP1408

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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