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General Information
Symbol
Dmel\Cdc42L89.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0123294
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: S89L.

A dominant negative form of Cdc42 is expressed under the control of UAS regulatory sequences.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of Cdc42L89.Scer\UAS driven by Scer\GAL4ptc-559.1 results in loss or stunting of epidermal hairs. When Cdc42L89.Scer\UAS is driven by Scer\GAL4Bx-MS1096, occasional multiple (but still stunted) wing hairs are seen. A reduction in wing size, formation of ectopic vein tissue and wing margin phenotypes. A strong bristle loss phenotype is seen in the wing margin which precludes observation of the width of the margin stripe. Small outgrowths in the wing surface are also seen.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
NOT Enhanced by
Statement
Reference
Suppressed by
NOT suppressed by
Statement
Reference
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (2)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Cdc42L89.Scer\UAS
Cdc42L89.UAS
Name Synonyms
Secondary FlyBase IDs
    References (4)