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General Information
Symbol
Dmel\Dsp1EP355
Species
D. melanogaster
Name
FlyBase ID
FBal0089430
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The P{EP} element is inserted within the 5' UTR.

Insertion components
P{EP}Dsp1EP355
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression using Scer\GAL4ey.PU does not induce a rough eye phenotype.

Mutant flies show a higher bacterial clearance activity than do control flies after injection with E.coli.

Mutant flies show a lower survival rate after infection with E.coli than do control flies.

Expression of Dsp1EP355 under the control of Scer\GAL4GMR.PF results in a weak rough eye phenotype.

Flies expressing Dsp1EP355 under the control of Scer\GAL4ap-md544 have a strong thoracic cleft and a deformed scutellum and wings.

Mutant larvae expressing Dsp1EP355 under the control of Scer\GAL4elav-C155 have ISN neuron pathfinding defects. Mutant larvae expressing Dsp1EP355 under the control of Scer\GAL4elav-C155 have reduced or abnormal synapses.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

The lower survival rate seen in Dsp1EP355 mutant flies after infection with E.coli is suppressed if the flies are also heterozygous for RelE20.

pnrMD237/+ adults expressing Dsp1EP355 under the control of Scer\GAL4pnr-MD237 have a strong thoracic and scutellar cleft.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer

Selected as: a P{EP} insertion line that modifies the pnrMD237/+ phenotype when expressed using Scer\GAL4pnr-MD237.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
bssEP355
Name Synonyms
Secondary FlyBase IDs
    References (10)