FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\chrbEP1035
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General Information
Symbol
Dmel\chrbEP1035
Species
D. melanogaster
Name
FlyBase ID
FBal0131394
Feature type
allele
Associated gene
Dmel\chrb
Associated Insertion(s)
P{EP}EP1035
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EP}EP1035
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of chrbEP1035 under the control of Scer\GAL4da.G32 results in an increase in mean life span compared to control flies. Lipid levels are significantly elevated in these flies.

      (Reiling and Hafen, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      chrbEP1035 is a suppressor of eye phenotype of AktUAS.cRa, Pdk1EP837, Scer\GAL4GMR.PF

      (Reiling and Hafen, 2004)
      NOT Suppressor of
      Statement
      Reference

      chrbEP1035/scylEP22.1, Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of RhebEP50.084-loxP, Scer\GAL4GMR.PF

      (Reiling and Hafen, 2004)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The large eye phenotype caused by co-expression of Akt1Scer\UAS.cRa and Pk61CEP837 under the control of Scer\GAL4GMR.PF is suppressed by co-expression of chrbEP1035. The large eye phenotype caused by co-expression of Akt1Scer\UAS.cRa and Pk61CEP837 under the control of Scer\GAL4GMR.PF is suppressed nearly to wild type by simultaneous co-expression of both scylEP22.1 and chrbEP1035. The bulging eye phenotype caused by expression of RhebEP50.084-loxP under the control of Scer\GAL4GMR.PF is not suppressed by simultaneous coexpression of both scylEP22.1 and chrbEP1035.

      (Reiling and Hafen, 2004)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a P{EP} insertion line that modifies the pnrMD237/+ phenotype when expressed using Scer\GAL4pnr-MD237.

      (Pena-Rangel et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      charybdeEP1035
      (Pena-Rangel et al., 2002)
      chrbEP1035
      Name Synonyms
      Secondary FlyBase IDs
        References (3)