FlyBase Allele Report: Scer\GAL4[EB1]

General Information

Symbol

Scer\GAL4^EB1

Species

S. cerevisiae

Name

FlyBase ID

FBal0134165

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}EB1

Carried in Construct

Also Known As

EB1-GAL4, EB1, GAL4-EB1, EB-GAL4

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GawB}EB1

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

Additional Information

Statement

Reference

Drives expression in the median and outer outer layers of the ellipsoid body, ring neurons R2 and R4m.

(FlyBase Curators, 2017)

Marker for

adult ellipsoid body ring neuron R2

(Thran et al., 2013)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior | adult stage, with TBPH^RNAi.UAS.cDa

(Diaper et al., 2013)

abnormal neuroanatomy | adult stage | progressive, with TBPH^RNAi.UAS.cDa

(Diaper et al., 2013)

increased sleep | adult stage, with dco^GD1259

(Wang et al., 2022)

Phenotype Manifest In

adult ellipsoid body ring neuron | progressive, with TBPH^RNAi.UAS.cDa

(Diaper et al., 2013)

Detailed Description

Statement

Reference

Inhibition (using shi^1.UAS at 32[o]C) of Scer\GAL4^EB1 cells in adults does not affect startle-induced climbing behavior, compared to controls.

Thermogenetic activation (using TrpA1^UAS.(B).cKa at 32[o]C) of Scer\GAL4^EB1 cells in adults does not affect startle-induced climbing behavior, compared to controls.

(Sun et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^EB1/bs^UAS.cHa rescues bs²

(Thran et al., 2013)

Scer\GAL4^EB1/ebo^UAS.cTa rescues ebo⁶⁷⁸

(Thran et al., 2013)

Fails to rescue

Ptpmeg^UAS.cWa/Scer\GAL4^EB1 fails to rescue Ptpmeg¹

(Whited et al., 2007)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

44409

y¹ w^*; βTub60D^Pin-1/CyO; P{GawB}EB1

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^EB1

Name Synonyms

Secondary FlyBase IDs

References (29)

Report Sections

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