Flies expressing wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^αTub84B.PL rescue the lethality and third instar larval wing disc overgrowth phenotypes seen in ft⁸/ft^G-rv mutants, but the wing hair phenotypes are still present. Rather than pointing distally as in wild type, the wing hairs in these flies are misoriented and swirling patterns can be observed. A strong planar cell polarity defect is also seen in the abdominal hairs and the wing anterior-posterior crossvein distance is reduced.

Expression of ft^T:SV5\V5 fully rescues the planar cell polarity defects seen in ft⁸/ft^G-rv mutant wings and abdomens expressing wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^αTub84B.PL. The reduced anterior-posterior crossvein distance phenotype is also suppressed.

Flies expressing ft^{ΔEGF.T:SV5\V5} (co-expressed with wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^αTub84B.PL) in a ft⁸/ft^G-rv mutant background do not exhibit any wing phenotypes compared to flies expressing wts^{Scer\UAS.T:Hsap\MYC} alone.

Expression of ft^{ΔICD.T:SV5\V5} partially rescues the planar cell polarity defects seen in ft⁸/ft^G-rv mutant wings and abdomens expressing wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^αTub84B.PL. The reduction in anterior-posterior crossvein distance appears to be partially rescued, although crossveins are often incomplete, making it difficult to calculate. The abdominal and wing hair polarity defects are also partially suppressed.

Expression of wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Act.PU does not suppress the head overgrowth seen in mop^sfv3 Df(3L)H99 mutant clones (generated in a minute background).

Expression of Tao^KK108458 has no effect on the reduction in eye size seen when wts^{Scer\UAS.T:Hsap\MYC} is expressed under the control of Scer\GAL4^GMR.PF.

The lethality and overgrowth phenotypes of ft^G-rv/ft⁸ animals are rescued by Scer\GAL4^tub.PU-mediated overexpression of wts^{Scer\UAS.T:Hsap\MYC}. However, these animals still show obvious planar cell polarity phenotypes in multiple tissues.

The lethality and overgrowth phenotypes of dco³ animals are rescued by Scer\GAL4^tub.PU-mediated overexpression of wts^{Scer\UAS.T:Hsap\MYC}, resulting in animals that, aside from some mild wing vein phenotypes, are indistinguishable from wild type animals over-expressing wts^{Scer\UAS.T:Hsap\MYC}.

Co-expression of yki^{S111A.S250A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with very small eyes.

Co-expression of yki^{S168A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with enlarged eyes.

Co-expression of yki^{S111A.S168A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG}).

Co-expression of yki^{S168A.S250A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with greatly enlarged eyes (but less so than in the absence of wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG}).

Co-expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^GMR.PF results in flies with enlarged and highly folded eyes.

Clones in the wing disc co-expressing yki^{S111A.S250A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^Act5C.PI do not survive well.

Large round clones are still observed in the wing disc when yki^{S168A.Scer\UAS.T:SV5\V5} is co-expressed with wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^Act5C.PI in the clones.

Co-expression of ex^Scer\UAS.cBa in clones expressing yki^{S168A.Scer\UAS.T:SV5\V5}, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^Act5C.PI decreases the size and number of clones recovered in the wing disc.

Clones co-expressing yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} ex^Scer\UAS.cBa, wts^{Scer\UAS.T:Hsap\MYC} and hpo^{Scer\UAS.T:Zzzz\FLAG} under the control of Scer\GAL4^Act5C.PI in the wing disc are large and round.

Clones of cells in the wing or eye disc in which wts^{Scer\UAS.T:Hsap\MYC}, hpo^{Scer\UAS.T:Zzzz\FLAG} and ex^Scer\UAS.cBa are over-expressed together with yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} generally overgrow compared to control clones, but can be less overgrown than yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5}-expressing clones alone. This is most evident in the wing pouch.

The overgrowth and folding of the eye disc induced by Scer\GAL4^GMR.PU-mediated expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} is largely suppressed by co-expression of wts^{Scer\UAS.T:Hsap\MYC}, hpo^{Scer\UAS.T:Zzzz\FLAG} and ex^Scer\UAS.cBa.

The overgrowth and folding of the eye disc induced by Scer\GAL4^GMR.PU-mediated expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} is not suppressed by co-expression of wts^{Scer\UAS.T:Hsap\MYC} alone, nor by co-expression of wts^{Scer\UAS.T:Hsap\MYC} and ex^Scer\UAS.cBa together.

The overgrowth and folding of the eye disc induced by Scer\GAL4^GMR.PU-mediated expression of yki^{S111A.S168A.S250A.Scer\UAS.T:SV5\V5} is partly suppressed by co-expression of wts^{Scer\UAS.T:Hsap\MYC}, hpo^{Scer\UAS.T:Zzzz\FLAG} together.

Clones co-expressing hpo^{Scer\UAS.T:Zzzz\FLAG} and wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Act5C.PI are not recovered in the wing disc.

Clones co-expressing hpo^{Scer\UAS.T:Zzzz\FLAG}, yki^{S168A.Scer\UAS.T:Avic\GFP-EGFP,T:Ivir\HA1} and wts^{Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Act5C.PI are not recovered in the wing disc.