FlyBase Allele Report: Dmel\cno[UAS.cBa]

General Information

Symbol

Dmel\cno^UAS.cBa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Boettner

FlyBase ID

FBal0152061

Feature type

allele

Associated gene

Dmel\cno

Associated Insertion(s)

Carried in Construct

P{UAS-cno.B}

Also Known As

UAS-cno^WT

Key Links

Transgenic product class

wild_type

(Boettner et al., 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Boettner et al., 2003)

Mutagen

in vitro construct

(Boettner et al., 2003)

Progenitor genotype

Carried in construct

P{UAS-cno.B}

Cytology

Description

UASt regulatory sequences drive expression of wild-type cno.

(Boettner et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

cno

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal, with Scer\GAL4^en.PU

(Boettner and Van Aelst, 2007)

Phenotype Manifest In

embryo | dorsal closure stage, with Scer\GAL4^ptc-559.1

(Boettner et al., 2003)

Detailed Description

Statement

Reference

Embryos expressing cno^Scer\UAS.cBa under the control of Scer\GAL4^ptc-559.1 do not show dorsal closure defects, but have defects in head involution.

(Boettner et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a suppressor | somatic clone of increased cell number | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a suppressor | somatic clone of neoplasia | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a suppressor | somatic clone of abnormal neuroanatomy | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a suppressor | somatic clone of abnormal size | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of increased mortality during development phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of abnormal cell migration | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

cno^UAS.cBa, Scer\GAL4^ptc-559.1 is a suppressor | partially of lethal | embryonic stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^ptc-559.1

(Boettner et al., 2003)

NOT Suppressor of

Statement

Reference

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a non-suppressor | somatic clone of neoplasia | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a non-suppressor | somatic clone of abnormal neuroanatomy | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a non-suppressor | somatic clone of abnormal size | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a non-suppressor | somatic clone of increased cell number | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

Phenotype Manifest In

Suppressor of

Statement

Reference

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a suppressor | somatic clone of larval brain | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of embryo phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of embryonic/first instar larval cuticle | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

Scer\GAL4^VP16.PDZ-GEF/cno^UAS.cBa is a suppressor of ectoderm | embryonic stage phenotype of PDZ-GEF^k13720

(Boettner and Van Aelst, 2007)

cno^UAS.cBa, Scer\GAL4^ptc-559.1 is a suppressor | partially of embryo | dorsal closure stage phenotype of Rap1^{N17.UAS.Tag:MYC}, Scer\GAL4^ptc-559.1

(Boettner et al., 2003)

NOT Suppressor of

Statement

Reference

cno^UAS.cBa/Scer\GAL4^Dll-md23 is a non-suppressor | somatic clone of larval brain | somatic clone | third instar larval stage phenotype of cno^R2, scrib¹

(Rives-Quinto et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

The overgrowth and increased number of progenitor cells characteristic for cno^R2;scrib¹ clones is significantly suppressed by Scer\GAL4^Dll-md23-driven expression of cno^Scer\UAS.cBa in the mutant clones.

(Rives-Quinto et al., 2017)

The dorsal closure defects seen in embryos expressing R^{N17.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^ptc-559.1 are substantially rescued by co-expression of cno^Scer\UAS.cBa.

(Boettner et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Scer\GAL4^ptc-559.1/cno^UAS.cBa partially rescues cno²

(Boettner et al., 2003)

Comments

Expression of cno^Scer\UAS.cBa under the control of Scer\GAL4^ptc-559.1 almost completely rescues the dorsal closure defects seen in cno² embryos.

(Boettner et al., 2003)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

cno^Scer\UAS.cBa

cno^UAS.cBa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Boettner

(Boettner et al., 2003)

Secondary FlyBase IDs

References (3)

Report Sections

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