FlyBase Allele Report: Dmel\gpp[61A]

General Information

Symbol

Dmel\gpp^61A

Species

D. melanogaster

Name

FlyBase ID

FBal0155222

Feature type

allele

Associated gene

Dmel\gpp

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Shanower et al., 2005)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with Df(3R)WIN11)

(Shanower et al., 2005)

lethal (with gpp⁰³³⁴²)

(Shanower et al., 2005)

lethal (with gpp^IN1)

(Shanower et al., 2005)

lethal (with gpp^X)

(Shanower et al., 2005)

lethal (with gpp^XXV)

(Shanower et al., 2005)

lethal | recessive

(Shanower et al., 2005)

lethal - all die before end of P-stage (with gpp⁸)

(Shanower et al., 2005)

non-enhancer of variegation, with P{hsp26-pt-T}39C-4

(Shanower et al., 2005)

non-enhancer of variegation, with P{hsp26-pt-T}118E-10

(Shanower et al., 2005)

non-enhancer of variegation, with P{hsp26-pt-T}118E-12

(Shanower et al., 2005)

non-suppressor of variegation, with P{hsp26-pt-T}39C-4

(Shanower et al., 2005)

non-suppressor of variegation, with P{hsp26-pt-T}118E-10

(Shanower et al., 2005)

non-suppressor of variegation, with P{hsp26-pt-T}118E-12

(Shanower et al., 2005)

some die during pharate adult stage (with gpp⁸)

(Shanower et al., 2005)

suppressor of variegation, with P{hsp26-pt-T}39C-27

(Shanower et al., 2005)

suppressor of variegation, with P{hsp26-pt-T}39C-31

(Shanower et al., 2005)

suppressor of variegation, with P{hsp26-pt-T}39C-50

(Shanower et al., 2005)

suppressor of variegation, with P{hsp26-pt-T}39C-55

(Shanower et al., 2005)

suppressor of variegation, with P{hsp26-pt-T}39C-62

(Shanower et al., 2005)

suppressor of variegation, with P{hsp26-pt-T}39C-72

(Shanower et al., 2005)

suppressor of variegation, with P{hsp26-pt-T}Dyrk3^118E-15

(Shanower et al., 2005)

suppressor of variegation | partially, with P{hsp26-pt-T}39C-5

(Shanower et al., 2005)

visible (with gpp⁸)

(Shanower et al., 2005)

visible | dominant

(Shanower et al., 2005)

Phenotype Manifest In

abdominal sternite | male (with gpp⁸)

(Shanower et al., 2005)

abdominal tergite 4 | ectopic | male

(Shanower et al., 2005)

abdominal tergite 5 | male

(Shanower et al., 2005)

abdominal tergite 5 | male (with gpp⁸)

(Shanower et al., 2005)

arista (with gpp⁸)

(Shanower et al., 2005)

leg | ectopic (with gpp⁸)

(Shanower et al., 2005)

prothoracic tarsal segment 4 | male (with gpp^X)

(Shanower et al., 2005)

sex comb (with gpp⁸)

(Shanower et al., 2005)

sex comb (with gpp^X)

(Shanower et al., 2005)

sex comb | ectopic (with gpp^X)

(Shanower et al., 2005)

Detailed Description

Statement

Reference

Heterozygous males show a transformation of the A5 tergite into a tergite resembling that of A4. gpp^61A/gpp⁸ males show loss of A5 tergite coloration and additional sternite hairs. gpp^61A/gpp⁸ animals have an arista to leg transformation and males show a reduction in the number of sex comb teeth. Dissected gpp^61A/gpp^X male pupae show a reduction in the number of sex comb teeth and also have sex combs on the fourth tarsal segment of the first leg.

(Shanower et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

gpp[+]/gpp^61A is an enhancer of visible | dominant phenotype of Abd-B^M1

(Shanower et al., 2005)

Phenotype Manifest In

Enhancer of

Statement

Reference

gpp[+]/gpp^61A is an enhancer of male genitalia phenotype of Abd-B^M1

(Shanower et al., 2005)

Suppressor of

Statement

Reference

gpp[+]/gpp^61A is a suppressor of wing vein | ectopic phenotype of Snr1^E1

(Marenda et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

gpp^61A weakly suppresses the pairing-sensitive silencing seen in flies carrying P{Mcp-ff#13}101 and P{Mcp-w#14}AP-2^stummelbein in cis, but does not suppress the pairing-sensitive silencing seen in flies carrying P{Mcp-w#11}16 and P{Mcp-w#11}102 in cis or P{Mcp-wy#2}63 and P{Mcp-ff#15}30 in cis. The penetrance of the rotated genitalia phenotype seen in Abd-B^M1 males is enhanced if they are also heterozygous for gpp^61A. The enhancement is stronger if the gpp allele is inherited maternally.

(Shanower et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a mutation that dominantly suppresses pairing-sensitive silencing of the mini-w gene in P{Mcp-ff#10}5 or P{Fab7-w#un3}18.73.1.

(Shanower et al., 2005)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

gpp^61A

grappa^61A

(Becker et al., 2016)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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