Open Close
General Information
Symbol
Dmel\gpp61A
Species
D. melanogaster
Name
FlyBase ID
FBal0155222
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Heterozygous males show a transformation of the A5 tergite into a tergite resembling that of A4. gpp61A/gpp8 males show loss of A5 tergite coloration and additional sternite hairs. gpp61A/gpp8 animals have an arista to leg transformation and males show a reduction in the number of sex comb teeth. Dissected gpp61A/gppX male pupae show a reduction in the number of sex comb teeth and also have sex combs on the fourth tarsal segment of the first leg.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhancer of
Statement
Reference

gpp[+]/gpp61A is an enhancer | maternal effect of visible | dominant phenotype of Abd-BM1

Phenotype Manifest In
Enhancer of
Statement
Reference

gpp[+]/gpp61A is an enhancer | maternal effect of male genitalia phenotype of Abd-BM1

Suppressor of
Statement
Reference

gpp[+]/gpp61A is a suppressor of wing vein | ectopic phenotype of Snr1E1

Additional Comments
Genetic Interactions
Statement
Reference

gpp61A weakly suppresses the pairing-sensitive silencing seen in flies carrying P{Mcp-ff#13}101 and P{Mcp-w#14}AP-2stummelbein in cis, but does not suppress the pairing-sensitive silencing seen in flies carrying P{Mcp-w#11}16 and P{Mcp-w#11}102 in cis or P{Mcp-wy#2}63 and P{Mcp-ff#15}30 in cis. The penetrance of the rotated genitalia phenotype seen in Abd-BM1 males is enhanced if they are also heterozygous for gpp61A. The enhancement is stronger if the gpp allele is inherited maternally.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

Selected as: a mutation that dominantly suppresses pairing-sensitive silencing of the mini-w gene in P{Mcp-ff#10}5 or P{Fab7-w#un3}18.73.1.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
gpp61A
Name Synonyms
Secondary FlyBase IDs
    References (2)