FlyBase Allele Report: Dmel\gpp[8]

General Information

Symbol

Dmel\gpp⁸

Species

D. melanogaster

Name

FlyBase ID

FBal0175660

Feature type

allele

Associated gene

Dmel\gpp

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Shanower et al., 2005)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

enhancer of variegation, with P{hsp26-pt-T}39C-72

(Shanower et al., 2005)

lethal (with Df(3R)WIN11)

(Shanower et al., 2005)

lethal (with gpp^IN1)

(Shanower et al., 2005)

lethal (with gpp^X)

(Shanower et al., 2005)

lethal (with gpp^XXV)

(Shanower et al., 2005)

lethal - all die before end of P-stage (with gpp^61A)

(Shanower et al., 2005)

lethal - all die during embryonic stage | recessive

(Shanower et al., 2005)

non-enhancer of variegation, with P{hsp26-pt-T}39C-4

(Shanower et al., 2005)

non-enhancer of variegation, with P{hsp26-pt-T}118E-12

(Shanower et al., 2005)

non-enhancer of variegation, with P{hsp26-pt-T}Dyrk3^118E-15

(Shanower et al., 2005)

non-suppressor of variegation, with P{hsp26-pt-T}39C-4

(Shanower et al., 2005)

non-suppressor of variegation, with P{hsp26-pt-T}118E-12

(Shanower et al., 2005)

non-suppressor of variegation, with P{hsp26-pt-T}Dyrk3^118E-15

(Shanower et al., 2005)

some die during embryonic stage | recessive

(Shanower et al., 2005)

some die during pharate adult stage (with gpp^61A)

(Shanower et al., 2005)

suppressor of variegation, with P{hsp26-pt-T}39C-50

(Shanower et al., 2005)

suppressor of variegation | partially, with P{hsp26-pt-T}39C-5

(Shanower et al., 2005)

suppressor of variegation | partially, with P{hsp26-pt-T}39C-31

(Shanower et al., 2005)

suppressor of variegation | partially, with P{hsp26-pt-T}39C-62

(Shanower et al., 2005)

suppressor of variegation | partially, with P{hsp26-pt-T}118E-10

(Shanower et al., 2005)

visible (with gpp^61A)

(Shanower et al., 2005)

Phenotype Manifest In

abdominal sternite | male (with gpp^61A)

(Shanower et al., 2005)

abdominal tergite 5 | male (with gpp^61A)

(Shanower et al., 2005)

arista (with gpp^61A)

(Shanower et al., 2005)

leg | ectopic (with gpp^61A)

(Shanower et al., 2005)

sex comb (with gpp^61A)

(Shanower et al., 2005)

Detailed Description

Statement

Reference

gpp^61A/gpp⁸ males show loss of A5 tergite coloration and additional sternite hairs. gpp^61A/gpp⁸ animals have an arista to leg transformation and males show a reduction in the number of sex comb teeth.

(Shanower et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

gpp[+]/gpp⁸ is an enhancer of sex comb | ectopic phenotype of Pcl¹⁰

(Shanower et al., 2005)

gpp[+]/gpp⁸ is an enhancer of sex comb | ectopic phenotype of Scm^D1

(Shanower et al., 2005)

gpp[+]/gpp⁸ is an enhancer of sex comb | ectopic phenotype of Pc³

(Shanower et al., 2005)

gpp[+]/gpp⁸ is an enhancer of sex comb | ectopic phenotype of Sce¹

(Shanower et al., 2005)

Suppressor of

Statement

Reference

gpp⁸ is a suppressor of phenotype of hh^Mrt

(Shanower et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

gpp⁸ suppresses the pairing-sensitive silencing seen in flies carrying P{Mcp-ff#13}101 and P{Mcp-w#14}AP-2^stummelbein in cis, weakly suppresses the pairing-sensitive silencing seen in flies carrying P{Mcp-w#11}16 and P{Mcp-w#11}102 in cis and does not suppress the pairing-sensitive silencing seen in flies carrying P{Mcp-wy#2}63 and P{Mcp-ff#15}30 in cis.

(Shanower et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a suppressor of hh^Mrt.

(Shanower et al., 2005)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

gpp⁸

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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