FlyBase Allele Report: Dmel\Rox8[EY02351]

General Information

Symbol

Dmel\Rox8^EY02351

Species

D. melanogaster

Name

FlyBase ID

FBal0155954

Feature type

allele

Associated gene

Dmel\Rox8

Associated Insertion(s)

P{EPgy2}Rox8^EY02351

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(FlyBase, 1996-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}Rox8^EY02351

Cytology

Description

The P{EPgy2}Rox8^EY02351 insertion maps within both Rox8 and CG5986 (overlapping genes on opposite strands).

(FlyBase, 1996-)

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:24,048,239..24,048,239 [-]

(Guo et al., 2020, FlyBase, 1996-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cancer

modeled by hpo^KK101704

(Guo et al., 2020)

modeled by Ras85D^V12.UAS, l(2)gl⁴

(Guo et al., 2020)

modeled by wts^KK101055

(Guo et al., 2020)

modeled by yki^UAS.cUa

(Guo et al., 2020)

modeled by yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

modeled by yki^{UAS.UTR-M2.Tag:MYC}

(Guo et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased size | adult stage, with Scer\GAL4^nub.PU

(Guo et al., 2020)

visible | adult stage, with Scer\GAL4^nub.PU

(Guo et al., 2020)

Phenotype Manifest In

wing, with Scer\GAL4^nub.PU

(Guo et al., 2020)

Detailed Description

Statement

Reference

The expression of Rox8^EY02351 under the control of Scer\GAL4^nub.PU induces a small wing.

(Guo et al., 2020)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of increased size | adult stage phenotype of Scer\GAL4^ptc.PU, wts^KK101055

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor | partially of increased size | third instar larval stage phenotype of Scer\GAL4^ptc.PU, yki^{UAS.UTR-M1.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of neoplasia | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR-M1.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR-M1.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor | partially of increased size | third instar larval stage phenotype of Scer\GAL4^ptc.PU, yki^{UAS.UTR-M2.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of neoplasia | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR-M2.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR-M2.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of neoplasia | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor | partially of hyperplasia | third instar larval stage phenotype of Scer\GAL4^ptc.PU, yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor | partially of increased size | third instar larval stage phenotype of Scer\GAL4^ptc.PU, yki^UAS.cUa

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of increased size | adult stage phenotype of Scer\GAL4^GMR.PU, yki^UAS.cUa

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, yki^UAS.cUa

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of visible | adult stage phenotype of Scer\GAL4^ptc.PU, yki^UAS.cUa

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of increased size | adult stage phenotype of Scer\GAL4^ptc.PU, yki^UAS.cUa

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of increased size | adult stage phenotype of Scer\GAL4^GMR.PU, hpo^KK101704

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, hpo^KK101704

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of visible | adult stage phenotype of Scer\GAL4^ptc.PU, hpo^KK101704

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of increased size | adult stage phenotype of Scer\GAL4^ptc.PU, hpo^KK101704

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^Act.PU is a suppressor of neoplasia | somatic clone | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^Act.PU, l(2)gl⁴

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of increased size | adult stage phenotype of Scer\GAL4^GMR.PU, wts^KK101055

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of visible | adult stage phenotype of Scer\GAL4^GMR.PU, wts^KK101055

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of visible | adult stage phenotype of Scer\GAL4^ptc.PU, wts^KK101055

(Guo et al., 2020)

NOT Suppressor of

Statement

Reference

Rox8^EY02351, Scer\GAL4^ptc.PU is a non-suppressor | partially of increased size | third instar larval stage phenotype of Scer\GAL4^ptc.PU, yki^{UAS.UTR-M1.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351/mir-8^{sponge.V2.UAS.mCherry}, Scer\GAL4^GMR.PU is a non-suppressor of neoplasia | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351/mir-8^{sponge.V2.UAS.mCherry}, Scer\GAL4^GMR.PU is a non-suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

Phenotype Manifest In

Suppressor of

Statement

Reference

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, wts^KK101055

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of first basal wing cell phenotype of Scer\GAL4^ptc.PU, wts^KK101055

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR-M1.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor | partially of anterior-posterior compartment boundary of the wing disc phenotype of Scer\GAL4^ptc.PU, yki^{UAS.UTR-M2.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR-M2.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor | partially of anterior-posterior compartment boundary of the wing disc phenotype of Scer\GAL4^ptc.PU, yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, yki^UAS.cUa

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of first basal wing cell phenotype of Scer\GAL4^ptc.PU, yki^UAS.cUa

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor | partially of anterior-posterior compartment boundary of the wing disc phenotype of Scer\GAL4^ptc.PU, yki^UAS.cUa

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^GMR.PU is a suppressor | partially of eye phenotype of Scer\GAL4^GMR.PU, hpo^KK101704

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^ptc.PU is a suppressor of first basal wing cell phenotype of Scer\GAL4^ptc.PU, hpo^KK101704

(Guo et al., 2020)

Rox8^EY02351, Scer\GAL4^Act.PU is a suppressor of eye-antennal disc | somatic clone | larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^Act.PU, l(2)gl⁴

(Guo et al., 2020)

NOT Suppressor of

Statement

Reference

Rox8^EY02351, Scer\GAL4^ptc.PU is a non-suppressor of anterior-posterior compartment boundary of the wing disc phenotype of Scer\GAL4^ptc.PU, yki^{UAS.UTR-M1.Tag:MYC}

(Guo et al., 2020)

Rox8^EY02351/mir-8^{sponge.V2.UAS.mCherry}, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of Scer\GAL4^GMR.PU, yki^{UAS.UTR.Tag:MYC}

(Guo et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

15865

y¹ w^67c23; P{EPgy2}Rox8^EY02351 CG5986^EY02351

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Rox8^EP02351

(Guo et al., 2020)

Rox8^EY02351

(Guo et al., 2020)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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