FB2026_02 , released June 18, 2026
Allele: Dmel\armUAS.Tag:M(sev)
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General Information
Symbol
Dmel\armUAS.Tag:M(sev)
Species
D. melanogaster
Name
FlyBase ID
FBal0159485
Feature type
allele
Associated gene
Dmel\arm
Associated Insertion(s)
Carried in Construct
P{UAS-sev-arm}
Key Links
Transgenic product class
wild_type
(Thompson, 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Thompson, 2004)
Mutagen
in vitro construct
(Thompson, 2004)
Progenitor genotype
Carried in construct
P{UAS-sev-arm}
Cytology
Description

UAS regulatory sequences drive expression of the extracellular and transmembrane domains of sev (Tag:M(sev)) fused to the N-terminus of arm.

(Thompson, 2004)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
arm
Tagged with
Tag:M(sev)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ubiquitous expression of armScer\UAS.T:sev-TM in embryos using Scer\GAL4unspecified does not cause a cuticle phenotype.

      (Thompson, 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4da.G32/armUAS.Tag:M(sev) partially rescues arm2

      (Thompson, 2004)
      Fails to rescue

      Scer\GAL4arm.PS/armUAS.Tag:M(sev) fails to rescue arm4, armS12.Tag:MYC

      (Thompson, 2004)

      Scer\GAL4arm.PS/armUAS.Tag:M(sev) fails to rescue arm4, armS6.Tag:MYC

      (Thompson, 2004)
      Comments

      The "lawn of denticles" cuticle phenotype seen in embryos carrying armS6.T:Hsap\MYC in an arm4 background is not rescued by ubiquitous expression of armScer\UAS.T:sev-TM using Scer\GAL4arm.PS. The "lawn of denticles" cuticle phenotype seen in embryos carrying armS12.T:Hsap\MYC in an arm4 background is not rescued by ubiquitous expression of armScer\UAS.T:sev-TM using Scer\GAL4arm.PS. The "lawn of denticles" cuticle phenotype seen in arm2 embryos is substantially rescued by ubiquitous expression of armScer\UAS.T:sev-TM using Scer\GAL4da.G32 (stripes of naked cuticle are restored).

      (Thompson, 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      armScer\UAS.T:TM-sev
      armScer\UAS.T:sev-TM
      armUAS.Tag:M(sev)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)