FlyBase Allele Report: Dmel\Kap-α3[w73]

General Information

Symbol

Dmel\Kap-α3^w73

Species

D. melanogaster

Name

FlyBase ID

FBal0160264

Feature type

allele

Associated gene

Dmel\Kap-α3

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Amino acid replacement: ?159term.

(Mason et al., 2003)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

3R:9,576,674..9,576,674 [-]

Nucleotide change:

C9576674T

Amino acid change:

Q159term | Kap-alpha3-PA; Q159term | Kap-alpha3-PB; Q159term | Kap-alpha3-PC; Q159term | Kap-alpha3-PD

Reported amino acid change:

?159term

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Mason et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of larval stage (with Df(3R)GB104)

(Mason et al., 2003)

lethal - all die before end of larval stage (with Kap-α3^D93)

(Mason et al., 2003)

lethal - all die before end of larval stage (with Kap-α3^D165)

(Mason et al., 2003)

some die during larval stage (with Df(3R)GB104)

(Mason et al., 2003)

some die during larval stage (with Kap-α3^D93)

(Mason et al., 2003)

some die during larval stage (with Kap-α3^D165)

(Mason et al., 2003)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Kap-α3^w73/Kap-α3^D93 is rescued by Scer\GAL4^αTub84B.PL/Kap-α3^-UTR.UASp

(Mason et al., 2003)

Comments

Kap-α3^{-UTR.Scer\UAS.P\T}; Scer\GAL4^αTub84B.PL rescues and Kap-α3^D93/Kap-α3^w73 to fully viable, fertile adults.

(Mason et al., 2003)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Kap-α3^w73

α3^w73

(Mason et al., 2003)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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