FlyBase Allele Report: Dmel\Gug[2295]

General Information

Symbol

Dmel\Gug²²⁹⁵

Species

D. melanogaster

Name

FlyBase ID

FBal0176120

Feature type

allele

Associated gene

Dmel\Gug

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Kankel et al., 2004)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Gug²²⁹⁵/Gug[+] is an enhancer | maternal effect of partially lethal | heat sensitive phenotype of ftz⁵/ftz¹³

(Kankel et al., 2004)

Gug²²⁹⁵/Gug[+] is an enhancer of visible | dominant | homeotic phenotype of trx³

(Kankel et al., 2004)

Suppressor of

Statement

Reference

Gug²²⁹⁵ is a suppressor of visible | homeotic phenotype of Scr^Msc

(Kankel et al., 2004)

NOT Suppressor of

Statement

Reference

Gug²²⁹⁵/Gug[+] is a non-suppressor of visible | dominant phenotype of Antp^73b

(Kankel et al., 2004)

Gug²²⁹⁵/Gug[+] is a non-suppressor of visible | dominant phenotype of Antp^Ns

(Kankel et al., 2004)

Phenotype Manifest In

Enhancer of

Statement

Reference

Gug²²⁹⁵/Gug[+] is an enhancer of adult abdominal segment 4 | ectopic phenotype of trx³

(Kankel et al., 2004)

Gug²²⁹⁵/Gug[+] is an enhancer of adult abdominal segment 5 phenotype of trx³

(Kankel et al., 2004)

Suppressor of

Statement

Reference

Gug²²⁹⁵ is a suppressor of mesothoracic leg phenotype of Scr^Msc

(Kankel et al., 2004)

Gug²²⁹⁵ is a suppressor of prothoracic leg | ectopic phenotype of Scr^Msc

(Kankel et al., 2004)

NOT Suppressor of

Statement

Reference

Gug²²⁹⁵/Gug[+] is a non-suppressor of arista phenotype of Antp^73b

(Kankel et al., 2004)

Gug²²⁹⁵/Gug[+] is a non-suppressor of arista phenotype of Antp^Ns

(Kankel et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

Gug²²⁹⁵ dominantly enhances the lethality of ftz⁵/ftz¹³ animals at 26.5^oC (fewer animals survive to adulthood). This interaction is a maternal effect. The mutant arista phenotype seen in Antp^Ns/+ adults is unaffected if they are also heterozygous for Gug²²⁹⁵. The reduction in the number of sex comb teeth on the first leg seen in Df(3R)Scr/+ males is enhanced by heterozygosity for Gug²²⁹⁵. Gug²²⁹⁵/+ enhances the frequency of transformation of haltere to wing seen in Df(3L)brm11/+ flies.

(Kankel et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Gug⁰³⁹²⁸

(Kankel et al., 2004)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a dominant enhancer of the lethality of ftz⁵/ftz¹³ at 26.5^oC. Females containing clones homozygous for the Gug²²⁹⁵ chromosome fail to lay eggs, probably because of secondary mutations on the Gug²²⁹⁵ chromosome.

(Kankel et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Atro²²⁹⁵

(Kankel et al., 2004)

Gug²²⁹⁵

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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