FlyBase Allele Report: Dmel\dl[UAS.cHa]

General Information

Symbol

Dmel\dl^UAS.cHa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Huang

FlyBase ID

FBal0180204

Feature type

allele

Associated gene

Dmel\dl

Associated Insertion(s)

Carried in Construct

P{UAS-dl.H}

Also Known As

UAS-dl, UAS-Dorsal, UAS-dl.H

Key Links

Transgenic product class

wild_type

(Huang et al., 2005)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Huang et al., 2005)

Mutagen

in vitro construct

(Huang et al., 2005)

Progenitor genotype

Carried in construct

P{UAS-dl.H}

Cytology

Description

UASt sequences drive expression of full-length dl.

(Huang et al., 2005)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates carcinoma

modeled by scrib¹

(Katsukawa et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size | adult stage, with Scer\GAL4^r4

(Suzawa et al., 2019)

increased occurrence of cell division | embryonic stage 13, with Scer\GAL4^sim.PS

(Barros and Bossing, 2021)

visible | adult stage, with Scer\GAL4^r4

(Suzawa et al., 2019)

Phenotype Manifest In

embryonic/larval plasmatocyte | increased number, with Scer\GAL4^Cg.PA

(Huang et al., 2005)

ventral midline of embryo | embryonic stage 13, with Scer\GAL4^sim.PS

(Barros and Bossing, 2021)

wing, with Scer\GAL4^r4

(Suzawa et al., 2019)

Detailed Description

Statement

Reference

The expression of dl^UAS.cHa under the control of Scer\GAL4^sim.PS stimulates mitosis in the ventral midline of stage 13 embryos.

(Barros and Bossing, 2021)

The expression of dl^UAS.cHa under the control of Scer\GAL4^r4 results in a small but significant decrease in wing size, as compared to controls.

(Suzawa et al., 2019)

Overexpression of dl^Scer\UAS.cHa under the control of Scer\GAL4^Cg.PA causes an increase in the number of plasmatocytes in the hemolymph of third instar larvae compared to wild type, but does not increase levels of lamellocytes.

(Huang et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^sim.PS, dl^UAS.cHa has increased occurrence of cell division | embryonic stage 13 phenotype, suppressible by Scer\GAL4^sim.PS/hep^CA.UAS

(Barros and Bossing, 2021)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^sim.PS, dl^UAS.cHa has ventral midline of embryo | embryonic stage 13 phenotype, suppressible by Scer\GAL4^sim.PS/hep^CA.UAS

(Barros and Bossing, 2021)

NOT Enhancer of

Statement

Reference

dl^UAS.cHa, Scer\GAL4^Cg.PA is a non-enhancer of lamellocyte | increased number phenotype of Dif^UAS.cIa, Scer\GAL4^Cg.PA

(Huang et al., 2005)

dl^UAS.cHa, Scer\GAL4^Cg.PA is a non-enhancer of embryonic/larval hemocyte | increased number phenotype of Dif^UAS.cIa, Scer\GAL4^Cg.PA

(Huang et al., 2005)

dl^UAS.cHa, Scer\GAL4^Cg.PA is a non-enhancer of embryonic/larval plasmatocyte | increased number phenotype of Dif^UAS.cIa, Scer\GAL4^Cg.PA

(Huang et al., 2005)

NOT Suppressor of

Statement

Reference

dl^UAS.cHa, Scer\GAL4^Cg.PA is a non-suppressor of lamellocyte | increased number phenotype of Dif^UAS.cIa, Scer\GAL4^Cg.PA

(Huang et al., 2005)

dl^UAS.cHa, Scer\GAL4^Cg.PA is a non-suppressor of embryonic/larval plasmatocyte | increased number phenotype of Dif^UAS.cIa, Scer\GAL4^Cg.PA

(Huang et al., 2005)

dl^UAS.cHa, Scer\GAL4^Cg.PA is a non-suppressor of embryonic/larval hemocyte | increased number phenotype of Dif^UAS.cIa, Scer\GAL4^Cg.PA

(Huang et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Overexpression of Dif^Scer\UAS.cIa and dl^Scer\UAS.cHa, both under the control of Scer\GAL4^Cg.PA, causes the same hemocyte phenotype as when only Dif^Scer\UAS.cIa is expressed.

(Huang et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

9319

y¹ w^*; P{UAS-dl.H}2

9320

P{UAS-dl.H}1, y¹ w^*; sna^Sco/CyO, y⁺

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

dl^Scer\UAS.cHa

dl^UAS.cHa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Huang

(Huang et al., 2005)

Secondary FlyBase IDs

References (18)

Report Sections

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