FB2026_02 , released June 18, 2026
Allele: Scer\GAL4fru.P1.B
Open Close
General Information
Symbol
Scer\GAL4fru.P1.B
Species
S. cerevisiae
Name
FlyBase ID
FBal0181610
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
TI{GAL4}fruGAL4.P1.B
Carried in Construct
Also Known As
fruP1-GAL4, fruGal4, fru P1-Gal4
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
FLPase
(Manoli et al., 2005)
I-SceI
(Manoli et al., 2005)
ends-out gene targeting
(Manoli et al., 2005)
Progenitor genotype
Associated Insertion(s)
TI{GAL4}fruGAL4.P1.B
Cytology
Description

A complete GAL4 driver coding sequence has been inserted at the start of exon 2 of the fru gene. The first two codons of the fru[M] transcript have been removed, the start and stop codons of GAL4 are retained.

(Manoli et al., 2005)
Allele components
Component
Use(s)
Inserted element
TI{GAL4}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      pupal stage P6 -- pharate adult stage
      pupal brain | restricted
      (Manoli et al., 2005)
      adult ventral nerve cord | restricted
      (Manoli et al., 2005)
      pharate adult stage
      olfactory system | restricted
      (Manoli et al., 2005)
      antennal lobe glomerulus DA1
      (Manoli et al., 2005)
      antennal lobe glomerulus VA1v
      (Manoli et al., 2005)
      antennal lobe glomerulus VL2
      (Manoli et al., 2005)
      adult gamma Kenyon cell
      (Manoli et al., 2005)
      alpha/beta Kenyon cell
      (Manoli et al., 2005)
      pharate adult stage -- adult stage
      adult olfactory receptor neuron | subset
      (Manoli et al., 2005)
      adult stage
      antennal olfactory receptor neuron of trichoid sensillum | subset
      (Manoli et al., 2005)
      maxillary palp olfactory receptor neuron | subset
      (Manoli et al., 2005)
      Johnston organ neuron | subset
      (Manoli et al., 2005)
      gustatory receptor neuron of the labellum | subset
      (Manoli et al., 2005)
      prothoracic leg taste bristle chemosensory neuron | subset
      (Manoli et al., 2005)
      adult olfactory receptor neuron Or67d
      (Grosjean et al., 2011)
      antennal lobe glomerulus DA1
      (Grosjean et al., 2011)
      adult olfactory receptor neuron Or47b
      (Grosjean et al., 2011)
      antennal lobe glomerulus VA1v
      (Grosjean et al., 2011)
      adult olfactory receptor neuron Ir84a
      (Grosjean et al., 2011)
      antennal lobe glomerulus VL2a
      (Grosjean et al., 2011)
      Additional Information
      Statement
      Reference

      ScerGAL4fru.P1.B drives expression in a pattern that reproduces that of endogenous fru male-specific (fru[M]) isoforms.

      (Manoli et al., 2005)
       
      Marker for
      Reflects expression of
      fru
      (Grosjean et al., 2011, Manoli et al., 2005)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shits.FRT.stop.UAS at 30[o]C) of Scer\GAL4fru.P1.B neurons that also express Scer\FLP1ey.PU in adult females significantly reduces receptivity to mating, compared to controls; in males, courtship pulse song-induced locomotion is significantly reduced, compared to controls.

      (Vaughan et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (9)
      Reported As
      Symbol Synonym
      Scer\GAL4fru.P1.B
      Scer\GAL4fru.P1
      fru-GAL4(B)
      (Laflamme et al., 2014)
      fruGAL4(B)
      (Pan et al., 2012)
      fruGAL4
      (Hueston et al., 2016, Vaughan et al., 2014)
      fruGal4
      (Devineni et al., 2013)
      fruM-Gal4
      (Hampel et al., 2011)
      fruGAL4(B)
      (Pan et al., 2011)
      fruP1-GAL4
      (Grosjean et al., 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (17)