Homozygous clones in the pupal eye (analysed at 42 hours after puparium formation) result in ommatidia with cone cell abnormalities and abnormal numbers of photoreceptor cells.
Compared with wild-type controls, homozygous RbfΔ14 mutant cells in the eye disc show heightened sensitivity to apoptosis after treatment with ionising irradiation.
Cells at the dorsal-ventral boundary of the late third instar wing disc are normally insensitive to irradiation induced apoptosis but become sensitive to it if they are part of RbfΔ14 homozygous somatic clones. (40Gy of γ rays; assayed after 4 hours at 25oC). There is also a general increase in cell death throughout these clones.