FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\iav3621
Open Close
General Information
Symbol
Dmel\iav3621
Species
D. melanogaster
Name
FlyBase ID
FBal0191568
Feature type
allele
Associated gene
Dmel\iav
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Gong et al., 2004)
Progenitor genotype
Cytology
Description

Deletion of amino acid residues TFAQ from exon 3 of iav.

(Gong et al., 2004)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:6,815,594..6,815,605 [+]
Comment:

Deletion of 12 base pairs encoding amino acid residues TFAQ from exon 3 of iav.

(Gong et al., 2004)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The normal preference of third instar larvae for 17.5[o]C over 14[o]C in a two-way choice test is eliminated in iav3621 and iav3621/Df(1)pod1Δ17 larvae.

      (Kwon et al., 2010)

      Compared with wild-type, iav3621 mutants display impaired negative geotaxis behaviour in addition to their reduced general locomotion.

      The Johnston's organ of iav3621 mutant flies show impaired neural activity in response to body rotation.

      (Sun et al., 2009)

      Antennal sound-evoked potentials are absent in iav3621/Y males and iavK1/iav3621 females.

      (Gong et al., 2004)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      iav3621 is rescued by iav+t9.2

      (Gong et al., 2004)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Selected as: flies that are slow to recover from C02-induced anesthesia when heterozygous with iav1.

      (Gong et al., 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      References (13)