TRPV
transient receptor potential vanilloid channel - expressed in chordotonal neurons where it is involved in temperature preference - expressed in antenna were it is involved in hearing
Please see the JBrowse view of Dmel\iav for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.50
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\iav using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\iav in JBrowseBased on mapping of iav1; iavhypoB-1 mapped to 1-20.7.
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
iav is required in larvae for choosing the preferred temperature of 17.5[o]C over 14[o]C through avoidance of 14[o]C, and this behaviour is mediated by increases in the number of turns and turning angles at this lower temperature.
Mutant flies fail to become sensitized to cocaine.
Lower than normal octopamine levels, especially in extracts from adult heads with dopamine and norepinephrine levels apparently normal.
Allelism of iav1 to iavhypoB-1 shown by O'Dell and Burnet (1986) in open field tests of heterozygotes; they also note that both mutations are recessive.
Source for merge of: iav CG4536
Source for merge of: iav hypoB