Frederick Roth's group modeled relationships among GO terms to predict
gene function based on patterns of annotations. Using existing
annotations in FlyBase (from a snapshot taken in January 2002), they
predicted GO terms that should be assigned to 50 fly genes. The
predicted annotations were manually assessed and the predicted terms
that were scored 'known to be true' and were more specific than the
existing GO terms were included in FlyBase gene records.
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KEY:
NAME: Gene name
FBID: FBgn identifier for gene
GOID: Identifier of predicted GO term
TERM: Name of predicted GO term
SCORE: Rating of 1 to 3 for if the GO term is likely
1 = Known to be true.
2 = Known not to be true.
3 = Neither of the above.
NAME CG1268 FBID FBgn0035521 GOID GO:0000220 TERM C-hydrogen-transporting
ATPase V0 domain SCORE 1
NAME CG1268 FBID FBgn0035521 GOID GO:0000221 TERM C-hydrogen-transporting
ATPase V1 domain SCORE 2
NAME CG6905 FBID FBgn0035136 GOID GO:0003734 TERM F-small nuclear
ribonucleoprotein SCORE 3
NAME CG4980 FBID FBgn0039558 GOID GO:0003734 TERM F-small nuclear
ribonucleoprotein SCORE 3
NAME CG12775 FBID FBgn0032987 GOID GO:0003735 TERM F-structural protein of
ribosome SCORE 1
NAME CG12740 FBID FBgn0035422 GOID GO:0003735 TERM F-structural protein of
ribosome SCORE 1
NAME Hsf FBID FBgn0001222 GOID GO:0003773 TERM F-heat shock protein SCORE 2
NAME Ubi-p63E FBID FBgn0003943 GOID GO:0003773 TERM F-heat shock protein SCORE 3
NAME Thor FBID FBgn0022073 GOID GO:0003797 TERM F-antibacterial peptide SCORE 3
NAME REG FBID FBgn0029133 GOID GO:0004299 TERM F-proteasome endopeptidase
SCORE 3
NAME TyrR FBID FBgn0004514 GOID GO:0004984 TERM F-olfactory receptor SCORE 3
NAME lush FBID FBgn0020277 GOID GO:0004984 TERM F-olfactory receptor SCORE 3
NAME CG4536 FBID FBgn0029904 GOID GO:0004984 TERM F-olfactory receptor SCORE 3
NAME Tl FBID FBgn0003717 GOID GO:0005044 TERM F-scavenger receptor SCORE 3
NAME bnk FBID FBgn0004389 GOID GO:0005200 TERM F-structural protein of
cytoskeleton SCORE 1
NAME Cortactin FBID FBgn0025865 GOID GO:0005200 TERM F-structural protein of
cytoskeleton SCORE 1
NAME CG4415 FBID FBgn0031296 GOID GO:0005563 TERM F-transfer RNA SCORE 2
NAME CG6905 FBID FBgn0035136 GOID GO:0005570 TERM F-small nuclear RNA SCORE 2
NAME CG4980 FBID FBgn0039558 GOID GO:0005570 TERM F-small nuclear RNA SCORE 2
NAME Tbh FBID FBgn0010329 GOID GO:0005792 TERM C-microsome SCORE 3
NAME CG5235 FBID FBgn0036565 GOID GO:0005792 TERM C-microsome SCORE 3
NAME CG7495 FBID FBgn0037154 GOID GO:0005792 TERM C-microsome SCORE 3
NAME Cyp12a2 FBID FBgn0040476 GOID GO:0005792 TERM C-microsome SCORE 3
NAME Cyp450_U5csm FBID FBgn0044501 GOID GO:0005792 TERM C-microsome SCORE 3
NAME Pros28.2 FBID FBgn0011827 GOID GO:0005839 TERM C-20S core proteasome
SCORE 1
NAME CG1909 FBID FBgn0039911 GOID GO:0005892 TERM C-nicotinic
acetylcholine-gated receptor-channel SCORE 1
NAME CG7972 FBID FBgn0035843 GOID GO:0006371 TERM P-mRNA splicing SCORE 1
NAME CG5931 FBID FBgn0036548 GOID GO:0006371 TERM P-mRNA splicing SCORE 1
NAME CG14060 FBID FBgn0036683 GOID GO:0006371 TERM P-mRNA splicing SCORE 1
NAME CG4980 FBID FBgn0039558 GOID GO:0006371 TERM P-mRNA splicing SCORE 1
NAME l(2)01424 FBID FBgn0010488 GOID GO:0006413 TERM P-protein synthesis
initiation SCORE 1
NAME AGO1 FBID FBgn0026611 GOID GO:0006413 TERM P-protein synthesis initiation
SCORE 1
NAME CG12413 FBID FBgn0039588 GOID GO:0006413 TERM P-protein synthesis
initiation SCORE 1
NAME Ulp1 FBID FBgn0027603 GOID GO:0006514 TERM P-deubiquitylation SCORE 1
NAME trpγ FBID FBgn0032593 GOID GO:0006816 TERM P-calcium ion transport
SCORE 1
NAME kl-2 FBID FBgn0001313 GOID GO:0007018 TERM P-microtubule-based movement
SCORE 1
NAME shi FBID FBgn0003392 GOID GO:0007018 TERM P-microtubule-based movement
SCORE 3
NAME Cdic FBID FBgn0013761 GOID GO:0007018 TERM P-microtubule-based movement
SCORE 1
NAME unc-104 FBID FBgn0034155 GOID GO:0007018 TERM P-microtubule-based
movement SCORE 3
NAME CG1193 FBID FBgn0037375 GOID GO:0007018 TERM P-microtubule-based movement
SCORE 3
NAME CG10845 FBID FBgn0039246 GOID GO:0007018 TERM P-microtubule-based
movement SCORE 3
NAME CG6905 FBID FBgn0035136 GOID GO:0008248 TERM F-pre-mRNA splicing factor
SCORE 1
NAME Voila FBID FBgn0024917 GOID GO:0008527 TERM F-taste receptor SCORE 3
NAME PK19 FBID FBgn0044025 GOID GO:0008527 TERM F-taste receptor SCORE 3
NAME PK11 FBID FBgn0044026 GOID GO:0008527 TERM F-taste receptor SCORE 3
NAME syd FBID FBgn0024187 GOID GO:0008567 TERM F-dynein ATPase SCORE 3
NAME Dhc1 FBID FBgn0025441 GOID GO:0008567 TERM F-dynein ATPase SCORE 1
NAME Unc-76 FBID FBgn0040395 GOID GO:0008567 TERM F-dynein ATPase SCORE 3
NAME cnn FBID FBgn0013765 GOID GO:0008570 TERM F-myosin ATPase SCORE 1
NAME bip2 FBID FBgn0026262 GOID GO:0016251 TERM F-general RNA polymerase II
transcription factor SCORE 1