FlyBase Allele Report: Dmel\Dronc[KG02994]

General Information

Symbol

Dmel\Dronc^KG02994

Species

D. melanogaster

Name

FlyBase ID

FBal0193073

Feature type

allele

Associated gene

Dmel\Dronc

Associated Insertion(s)

P{SUPor-P}Dronc^KG02994

Carried in Construct

Also Known As

KG02994

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Chew et al., 2004)

Mutagen

Progenitor genotype

Associated Insertion(s)

P{SUPor-P}Dronc^KG02994

Cytology

Description

Insertion 113bp upstream of the 5' UTR.

(Daish et al., 2004)

Allele components

Component

Use(s)

Inserted element

P{SUPor-P}

insertional mutagenesis tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:9,968,330..9,968,330 [-]

(Waldhuber et al., 2005, Chew et al., 2004, Daish et al., 2004)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal developmental rate

(Daish et al., 2004)

lethal | recessive

(Daish et al., 2004)

Phenotype Manifest In

postalar bristle | increased number

(Chew et al., 2004)

Detailed Description

Statement

Reference

Nc^KG02994 homozygous adults exhibit postalar bristle duplication at a low penetrance (4%).

(Chew et al., 2004)

The survival rate of homozygotes to the third larval instar stage is decreased to 70% of expected and eclosion is delayed compared to controls.

(Daish et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Dronc^KG02994/Nc[+] is a suppressor | partially of visible phenotype of Lrrk^I1915T.UAS, Scer\GAL4^GMR.PF, foxo^UAS.cKb

(Kanao et al., 2010)

Phenotype Manifest In

Suppressor of

Statement

Reference

Dronc^KG02994/Nc[+] is a suppressor | partially of eye phenotype of Lrrk^I1915T.UAS, Scer\GAL4^GMR.PF, foxo^UAS.cKb

(Kanao et al., 2010)

Additional Comments

Genetic Interactions

Statement

Reference

The eye phenotype caused by co-expression of foxo^Scer\UAS.cKb and Lrrk^{I1915T.Scer\UAS} under the control of Scer\GAL4^GMR.PF is significantly suppressed by Nc^KG02994/+.

(Kanao et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

13338

y¹; P{SUPor-P}Dronc^KG02994 ry⁵⁰⁶/TM3, Sb¹ Ser¹

Kyoto

111539

y^d2 w¹¹¹⁸ P{ey-FLP.N}2 P{5xglBS-lacZ.38-1}TPN1; P{SUPor-P}Dronc^KG02994 P{neoFRT}80B/TM6B, P{Car20y}TPN1, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Dronc^G02994

(Kanao et al., 2010)

Dronc^KG02994

Nc^KG02994

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

Open Close