FlyBase Allele Report: Dmel\dpp[s-hc1]

General Information

Symbol

Dmel\dpp^s-hc1

Species

D. melanogaster

Name

FlyBase ID

FBal0193757

Feature type

allele

Associated gene

Dmel\dpp

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

gamma ray

Nature of the Allele

Allele class

Mutagen

gamma ray

(Stultz et al., 2006, Stultz et al., 2005)

Progenitor genotype

Cytology

Description

A 15bp deletion within the 3.5kb dpp head capsule enhancer.

(Stultz et al., 2012)

Carries a lesion in the 5'end of the dpp gene between nucleotides 62 and 64, within the shortvein cis-regulatory region.

(Stultz et al., 2006)

Small deletion of 10-50bp located at position 63.4 on the dpp molecular map (coordinates according to FBrf0051824).

(Stultz et al., 2005)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

2L:2,434,857..2,434,871 [+]

Comment:

A 15bp deletion within the 3.5kb dpp head capsule enhancer.

(Stultz et al., 2012)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die (with dpp^s7)

(Stultz et al., 2005)

viable

(Stultz et al., 2012, Stultz et al., 2005)

viable (with dpp^d5)

(Stultz et al., 2005)

viable (with dpp^d6)

(Stultz et al., 2005)

viable (with dpp^d12)

(Stultz et al., 2005)

viable (with dpp^s11)

(Stultz et al., 2005)

viable (with dpp^s13)

(Stultz et al., 2005)

viable (with dpp^s20)

(Stultz et al., 2005)

viable (with dpp^s22)

(Stultz et al., 2005)

visible

(Stultz et al., 2005)

visible (with dpp^s7)

(Stultz et al., 2005)

visible (with dpp^s11)

(Stultz et al., 2005)

visible (with dpp^s13)

(Stultz et al., 2005)

visible (with dpp^s20)

(Stultz et al., 2005)

visible (with dpp^s22)

(Stultz et al., 2005)

visible (with dpp^TgR46.1)

(Stultz et al., 2005)

Phenotype Manifest In

adult head capsule

(Stultz et al., 2012, Stultz et al., 2005)

adult head capsule (with dpp^s7)

(Stultz et al., 2005)

adult head capsule (with dpp^s11)

(Stultz et al., 2005)

adult head capsule (with dpp^s13)

(Stultz et al., 2005)

adult head capsule (with dpp^s20)

(Stultz et al., 2005)

adult head capsule (with dpp^s22)

(Stultz et al., 2005)

adult head capsule (with dpp^TgR46.1)

(Stultz et al., 2005)

Detailed Description

Statement

Reference

30% of dpp^s-hc1 mutants show disruption to the head capsule. Often the phenotype is only seen on ones side.

(Stultz et al., 2012)

100% viable. 30% of homozygotes have head capsule defects.

dpp^s-hc1/dpp^TgR46.1 adults have normal wings but show head capsule defects.

(Stultz et al., 2005)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Complements

dpp^s6

(Stultz et al., 2005)

dpp^d12

(Stultz et al., 2005)

dpp^d6

(Stultz et al., 2005)

dpp^d5

(Stultz et al., 2005)

Partially rescued by

Df(2L)DTD2/dpp^s-hc1 is partially rescued by dpp^Sal20

(Stultz et al., 2005)

Comments

dpp^s-hc1 fully complements the wing vein defects of dpp^s6.

(Stultz et al., 2005)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dpp^s-hc1

(Stultz et al., 2012, Lee et al., 2007, Stultz et al., 2006)

s-hc1

(Stultz et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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