FlyBase Allele Report: Dmel\Apc[GD1333]

General Information

Symbol

Dmel\Apc^GD1333

Species

D. melanogaster

Name

FlyBase ID

FBal0198735

Feature type

allele

Associated gene

Dmel\Apc

Associated Insertion(s)

Carried in Construct

P{GD1333}

Also Known As

UAS-apc^RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Dickson et al., 2007.7.18)

Mutagen

in vitro construct

(Dickson et al., 2007.7.18)

Progenitor genotype

Carried in construct

P{GD1333}

Cytology

Description

UASt regulatory sequences drive expression of an inverted repeat.

(Dickson et al., 2007.7.18)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-GD1333

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of intestinal cancer

CEA with Ras85D^V12.cUa.UAS, p53^GD4483

(Quintero and Bangi, 2023)

CEA with Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, p53^GD4483

(Quintero and Bangi, 2023)

CEA with Med^GD1483, Ras85D^V12.cUa.UAS, p53^GD4483

(Quintero and Bangi, 2023)

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

increased cell number | adult stage, with Scer\GAL4^esg.PU

(Kassel et al., 2025)

increased cell number | adult stage, with Scer\GAL4^NP7397

(Tian et al., 2017)

increased occurrence of cell division | somatic clone, with Scer\GAL4^Act.PU

(Tian et al., 2017)

increased size | adult stage, with Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

(Neely et al., 2010)

viable, with Scer\GAL4^Mef2.PR

(Schnorrer et al., 2010)

viable, with Scer\GAL4^tin.CΔ4

(Neely et al., 2010)

visible | adult stage, with Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

Phenotype Manifest In

adult cuticle | ectopic, with Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

adult head, with Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

adult midgut, with Scer\GAL4^esg.PU

(Kassel et al., 2025)

adult midgut epithelium

(Tian et al., 2017)

adult midgut epithelium | somatic clone, with Scer\GAL4^Act.PU

(Tian et al., 2017)

enteroblast | adult stage | increased number, with Scer\GAL4^NP7397

(Tian et al., 2017)

eye, with Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

intestinal stem cell | adult stage | increased number, with Scer\GAL4^NP7397

(Tian et al., 2017)

Detailed Description

Statement

Reference

Expression of Apc^GD1333 under the Scer\GAL4^esg-NP7397 driver (combined with tub-Gal80[ts] for temporal control) limited to either during the formation of adult midgut or after eclosion, i.e. during the gut homeostasis, results in both contexts in increased number of progenitor cells (intestinal stem cells, ISCs, and enteroblasts, EBs).

Clones of progenitor cells and their progeny in the posterior midgut (induced by the 'flip-out' method) expressing Apc^GD1333 driven by Scer\GAL4^Act.PU show increased number of mitotic cells compared to control clones.

(Tian et al., 2017)

Adults expressing Apc^GD1333 under the control of Scer\GAL4^elav.PLu (in the presence of Dcr-2^Scer\UAS.cDa to increase the efficiency of RNAi) do not show a significant defect in avoidance of noxious temperature (46[o]C) compared to control flies.

(Neely et al., 2010)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Apc^GD1333, Scer\GAL4^esg.PU has increased cell number | adult stage phenotype, non-enhanceable by wg^RNAi.UAS.cUa, Scer\GAL4^esg.PU

(Kassel et al., 2025)

Suppressed by

Statement

Reference

Apc^GD1333, Scer\GAL4^esg.PU has increased cell number | adult stage phenotype, suppressible by ctrip^GD10284, Scer\GAL4^esg.PU

(Kassel et al., 2025)

Apc^GD1333, Scer\GAL4^esg.PU has increased cell number | adult stage phenotype, suppressible by ctrip^KK100515, Scer\GAL4^esg.PU

(Kassel et al., 2025)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype, suppressible | partially by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype, suppressible | partially by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | adult stage | somatic clone - tissue specific phenotype, suppressible by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | adult stage | somatic clone - tissue specific phenotype, suppressible by Tk^JF01818, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | adult stage | somatic clone - tissue specific phenotype, suppressible by Tk^JF01818, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype, suppressible | partially by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype, suppressible by InR^GL00139, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype, suppressible | partially by InR^GL00139, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype, suppressible | partially by TkR99D^JF02663, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype, suppressible by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Scer\GAL4^NP7397 has increased cell number | adult stage phenotype, suppressible by ebd1^GD10952, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has increased cell number | adult stage phenotype, suppressible by ebd1^JF02926, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has increased cell number | adult stage phenotype, suppressible by ewg^JF01569, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has increased cell number | adult stage phenotype, suppressible by ewg^JF01783, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU has visible | adult stage phenotype, suppressible by amls^UAS.C-Tag:HA, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

Apc^GD1333, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU has increased size | adult stage phenotype, suppressible by amls^UAS.C-Tag:HA, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

NOT suppressed by

Statement

Reference

Apc^GD1333, Scer\GAL4^esg.PU has increased cell number | adult stage phenotype, non-suppressible by wg^RNAi.UAS.cUa, Scer\GAL4^esg.PU

(Kassel et al., 2025)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | adult stage | somatic clone - tissue specific phenotype, non-suppressible by Tk^JF01818, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype, non-suppressible by InR^GL00139, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype, non-suppressible by InR^GL00139, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype, non-suppressible by InR^GL00139, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | somatic clone - tissue specific phenotype, non-suppressible by InR^GL00139, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype, non-suppressible by TkR99D^JF02663, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype, non-suppressible by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype, non-suppressible by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | adult stage | somatic clone - tissue specific phenotype, non-suppressible by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | adult stage | somatic clone - tissue specific phenotype, non-suppressible by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

NOT Enhancer of

Statement

Reference

Scer\GAL4^GMR.PU/Apc^GD1333 is a non-enhancer of abnormal neurophysiology | adult stage phenotype of mir-210^Δ

(Weigelt et al., 2019)

Apc^GD1333, Scer\GAL80^ts.αTub84B, Scer\GAL4^da.PU is a non-enhancer of lethal - all die during pupal stage | heat sensitive phenotype of Scer\GAL4^da.PU, Scer\GAL80^ts.αTub84B, fzr^RNAi.UAS.WIZ

(Neuert et al., 2017)

NOT Suppressor of

Statement

Reference

Scer\GAL4^GMR.PU/Apc^GD1333 is a non-suppressor of abnormal neurophysiology | adult stage phenotype of mir-210^Δ

(Weigelt et al., 2019)

Apc^GD1333, Scer\GAL80^ts.αTub84B, Scer\GAL4^da.PU is a non-suppressor of lethal - all die during pupal stage | heat sensitive phenotype of Scer\GAL4^da.PU, Scer\GAL80^ts.αTub84B, fzr^RNAi.UAS.WIZ

(Neuert et al., 2017)

Other

Statement

Reference

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has short lived | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased occurrence of cell division | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has short lived | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has short lived | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell growth rate | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased occurrence of cell division | cell non-autonomous | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has abnormal cell number | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased cell size | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has increased occurrence of cell division | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Apc^GD1333, Scer\GAL4^esg.PU has adult midgut phenotype, non-enhanceable by wg^RNAi.UAS.cUa, Scer\GAL4^esg.PU

(Kassel et al., 2025)

Suppressed by

Statement

Reference

Apc^GD1333, Scer\GAL4^esg.PU has adult midgut phenotype, suppressible by ctrip^GD10284, Scer\GAL4^esg.PU

(Kassel et al., 2025)

Apc^GD1333, Scer\GAL4^esg.PU has adult midgut phenotype, suppressible by ctrip^KK100515, Scer\GAL4^esg.PU

(Kassel et al., 2025)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has adult enteroendocrine cell | increased number | somatic clone - tissue specific phenotype, suppressible by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has adult enteroendocrine cell | increased number | somatic clone - tissue specific phenotype, suppressible | partially by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has intestinal stem cell | increased number | cell non-autonomous | adult stage | somatic clone - tissue specific phenotype, suppressible | partially by Tk^JF01818, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has intestinal stem cell | increased number | cell non-autonomous | adult stage | somatic clone - tissue specific phenotype, suppressible | partially by TkR99D^JF02663, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Scer\GAL4^NP7397 has adult midgut epithelium phenotype, suppressible by ebd1^GD10952, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has intestinal stem cell | increased number | adult stage phenotype, suppressible by ebd1^GD10952, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has enteroblast | increased number | adult stage phenotype, suppressible by ebd1^GD10952, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has adult midgut epithelium phenotype, suppressible by ebd1^JF02926, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has intestinal stem cell | increased number | adult stage phenotype, suppressible by ebd1^JF02926, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has enteroblast | increased number | adult stage phenotype, suppressible by ebd1^JF02926, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has adult midgut epithelium phenotype, suppressible by ewg^JF01569, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has intestinal stem cell | increased number | adult stage phenotype, suppressible by ewg^JF01569, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has enteroblast | increased number | adult stage phenotype, suppressible by ewg^JF01569, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has adult midgut epithelium phenotype, suppressible by ewg^JF01783, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has intestinal stem cell | increased number | adult stage phenotype, suppressible by ewg^JF01783, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^NP7397 has enteroblast | increased number | adult stage phenotype, suppressible by ewg^JF01783, Scer\GAL4^NP7397

(Tian et al., 2017)

Apc^GD1333, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU has eye phenotype, suppressible by amls^UAS.C-Tag:HA, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

Apc^GD1333, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU has adult cuticle | ectopic phenotype, suppressible by amls^UAS.C-Tag:HA, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

Apc^GD1333, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU has adult head phenotype, suppressible by amls^UAS.C-Tag:HA, Scer\GAL4^GMR.PU, Scer\GAL4^ey.PU

(Reim et al., 2014)

NOT suppressed by

Statement

Reference

Apc^GD1333, Scer\GAL4^esg.PU has adult midgut phenotype, non-suppressible by wg^RNAi.UAS.cUa, Scer\GAL4^esg.PU

(Kassel et al., 2025)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has adult enteroendocrine cell | increased number | somatic clone - tissue specific phenotype, non-suppressible by sc^JF02104, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has intestinal stem cell | increased number | cell non-autonomous | adult stage | somatic clone - tissue specific phenotype, non-suppressible by Pten^RNAi.UAS.cUa, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has intestinal stem cell | increased number | cell non-autonomous | adult stage | somatic clone - tissue specific phenotype, non-suppressible by InR^GL00139, Scer\GAL4^{Act5C.PS-FRT3}

(Quintero and Bangi, 2023)

NOT Enhancer of

Statement

Reference

Scer\GAL4^GMR.PU/Apc^GD1333 is a non-enhancer of retina phenotype of mir-210^Δ

(Weigelt et al., 2019)

NOT Suppressor of

Statement

Reference

Scer\GAL4^GMR.PU/Apc^GD1333 is a non-suppressor of retina phenotype of mir-210^Δ

(Weigelt et al., 2019)

Other

Statement

Reference

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has intestinal stem cell | increased number | cell non-autonomous | adult stage | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has adult enteroendocrine cell | increased number | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Pten^RNAi.UAS.cUa, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has adult enterocyte | increased number | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Med^GD1483, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has adult enteroendocrine cell | increased number | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has adult enteroendocrine cell | increased number | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Apc^GD1333, Ras85D^V12.cUa.UAS, Scer\GAL4^{Act5C.PS-FRT3}, p53^GD4483 has adult enterocyte | increased number | somatic clone - tissue specific phenotype

(Quintero and Bangi, 2023)

Additional Comments

Genetic Interactions

Statement

Reference

The increased number of progenitor cells (intestinal stem cells and enteroblasts) observed in adult flies expressing Apc^GD1333 under the control of Scer\GAL4^esg-NP7397 is fully suppressed by co-expression of any of the following: ebd1^GD10952, ebd1^JF02926, ewg^JF01569 or ewg^JF01783.

(Tian et al., 2017)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

VDRC

v51468

w¹¹¹⁸; P{GD1333}v51468

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Apc^GD1333

Name Synonyms

Secondary FlyBase IDs

References (13)

Report Sections

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